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NCT00198094 · ClinicalTrials.gov registry record · Phase 4
A Study of Sertraline and Early Alprazolam XR Administration Versus Sertraline Only in Panic Disorder Patients
A Phase 4 study, sponsored by Indiana University.
- Completed
- Registry status
- Phase 4
- Development phase
- 150
- Enrollment target
NCT00198094: Completed Phase 4 study, sponsored by Indiana University.
NCT00198094 is a Phase 4 study that has completed, run by Indiana University. The registered enrollment target is 150 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00198094, a Phase 4 study, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 150 participants
- Enrollment target
Study Summary
The primary objective for the study is to test the hypothesis that sertraline plus alprazolam XR will result in superior early stabilization of primary care PD patients versus sertraline/placebo over a 12-week treatment period. The secondary objectives of the study are a) to assess withdrawal symptoms during alprazolam XR taper (weeks 5-7 of the 12-week trial) and after discontinuation, b) to compare physical health outcomes, medical services utilization, and cost-effectiveness of the two study interventions across the 12-week treatment period and subsequent three month maintenance treatment with sertraline alone, and c) to assess whether early co-administration of sertraline/ alprazolam XR will result in greater maintenance of treatment response than sertraline/placebo over the three months following the 12 week acute treatment program.
Interventions
- DRUG Sertraline and Alprazolam XR
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2003-12 |
| Est. Completion | 2007-09 |
| Phase | Phase 4 |
What the finished NCT00198094 record still lists
NCT00198094 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 1 intervention - of which Sertraline and Alprazolam XR is the first listed.
NCT00198094 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00198094 about?
NCT00198094 is a clinical study titled "A Study of Sertraline and Early Alprazolam XR Administration Versus Sertraline Only in Panic Disorder Patients". The primary objective for the study is to test the hypothesis that sertraline plus alprazolam XR will result in superior early stabilization of primary care PD patients versus sertraline/placebo over a 12-week treatment period. The secondary objectives of the study are a) to assess withdrawal sympto...
What is the current status of trial NCT00198094?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 150 participants. The study started on 2003-12. Estimated completion is 2007-09.
What interventions are being tested in trial NCT00198094?
The interventions under investigation include: Sertraline and Alprazolam XR (DRUG).
Who is sponsoring clinical trial NCT00198094?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00198094's enrollment target sits among peer trials
150 533rd of 2000 higher than 1,436 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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