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NCT00193206 · ClinicalTrials.gov registry record · Phase 2

Neo-adjuvant Gemcitabine, Epirubicin, ABI-007 (GEA) in Locally Advanced or Inflammatory Breast Cancer

A Phase 2 study, sponsored by SCRI Development Innovations.

Completed
Registry status
Phase 2
Development phase
123
Enrollment target

NCT00193206: Completed Phase 2 study, sponsored by SCRI Development Innovations.

NCT00193206 is a Phase 2 study that has completed, run by SCRI Development Innovations. The registered enrollment target is 123 participants, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00193206, a Phase 2 study, has completed, sponsored by SCRI Development Innovations.

COMPLETED
Registry status
Phase 2
Development phase
123 participants
Enrollment target

Study Summary

In this trial we will evaluate ABI-007 with gemcitabine and epirubicin, utilizing the biweekly pegfilgrastim support, in order to further improve upon the effectiveness and favorable toxicity of this triplet.

Primary Outcome

For the purpose of this study, a pathologic complete response (pCR) was defined as no evidence of residual invasive tumor in the breast (pT0) and axillary lymph nodes (pN0), gross or microscopic, in the sample removed at the time of surgical resection. Residual ductal or lobular carcinoma in situ was not considered in pCR assessments. Percentage of participants who experienced pCR is reported.

Interventions

  • DRUG Gemcitabine
  • DRUG Epirubicin
  • DRUG Albumin-bound Paclitaxel

Trial Details

FieldValue
Enrollment Target 123 participants
Start Date 2005-09
Est. Completion 2009-05
Phase Phase 2
SCRI Development Innovations

146 total trials

What the finished NCT00193206 record still lists

NCT00193206 is an interventional study that assigns participants to a tested intervention. The registered 123 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target.

The record links to 0 conditions, and to 3 interventions - of which Gemcitabine is the first listed.

NCT00193206 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00193206 about?

NCT00193206 is a clinical study titled "Neo-adjuvant Gemcitabine, Epirubicin, ABI-007 (GEA) in Locally Advanced or Inflammatory Breast Cancer". In this trial we will evaluate ABI-007 with gemcitabine and epirubicin, utilizing the biweekly pegfilgrastim support, in order to further improve upon the effectiveness and favorable toxicity of this triplet.

What is the current status of trial NCT00193206?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 123 participants. The study started on 2005-09. Estimated completion is 2009-05.

What interventions are being tested in trial NCT00193206?

The interventions under investigation include: Gemcitabine (DRUG), Epirubicin (DRUG), Albumin-bound Paclitaxel (DRUG).

Who is sponsoring clinical trial NCT00193206?

This trial is sponsored by SCRI Development Innovations, which has 146 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00193206's enrollment target sits among peer trials

123 564th of 2000 higher than 1,436 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00193206, the US trial registry maintained by the National Library of Medicine. NCT00193206 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.