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NCT00189163 · ClinicalTrials.gov registry record · Phase 4
Pioglitazone in Hepatitis C
A Phase 4 study of Chronic Hepatitis C, sponsored by University of Michigan.
- Completed
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT00189163: Completed Phase 4 study of Chronic Hepatitis C, sponsored by University of Michigan.
NCT00189163 is a Phase 4 study of Chronic Hepatitis C that has completed, run by University of Michigan. The registered enrollment target is 40 participants, below the 212-participant average among 16 other Chronic Hepatitis C trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00189163, a Phase 4 study of Chronic Hepatitis C, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
The presence of insulin resistance (IR) appears to be a key factor in the development of steatosis and disease progression in patience with Hepatitis C virus (HCV) genotype-1 infections similar to levels in Non-alcoholic fatty liver disease (NAFLD). The objective of this study is to determine whether Pioglatizone, when given along with Interferon and Ribavirin, reduces insulin resistance and lowers HCV viral levels and improved response in patients who have HCV genotype-1 infection when compared to a placebo.
Primary Outcome
Measuring HCV RNA in serum (detectable or undetectable)
Conditions Studied
Interventions
- DRUG Pioglitazone
- DRUG Placebo Oral Tablet
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2005-01 |
| Phase | Phase 4 |
What the finished NCT00189163 record still lists
NCT00189163 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 212-participant average among 16 other Chronic Hepatitis C trials with a reported enrollment target (81% lower).
The record links to 1 condition, with Chronic Hepatitis C appearing as the primary indexed condition, and to 2 interventions - of which Pioglitazone is the first listed.
NCT00189163 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT00189163 about?
NCT00189163 is a clinical study titled "Pioglitazone in Hepatitis C". The presence of insulin resistance (IR) appears to be a key factor in the development of steatosis and disease progression in patience with Hepatitis C virus (HCV) genotype-1 infections similar to levels in Non-alcoholic fatty liver disease (NAFLD). The objective of this study is to determine whethe...
What is the current status of trial NCT00189163?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2005-01.
What conditions does trial NCT00189163 study?
This clinical trial studies the following conditions: Chronic Hepatitis C.
What interventions are being tested in trial NCT00189163?
The interventions under investigation include: Pioglitazone (DRUG), Placebo Oral Tablet (DRUG).
Who is sponsoring clinical trial NCT00189163?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00189163 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Hepatitis C
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00189163's enrollment target sits among peer trials
40 9th of 16 higher than 7 of 16 other Chronic Hepatitis C trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Hepatitis C trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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