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NCT00187447 · ClinicalTrials.gov registry record · Phase 2
Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus
A Phase 2 study, sponsored by University of California, San Francisco.
- Completed
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT00187447: Completed Phase 2 study, sponsored by University of California, San Francisco.
NCT00187447 is a Phase 2 study that has completed, run by University of California, San Francisco. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00187447, a Phase 2 study, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
The purpose of this study is to examine if a higher dose of indomethacin will increase the rate of ductus arteriosus closure in extremely premature infants without increasing the side effects. The long term objective is to find the optimal dosing of indomethacin for permanent closure of the Ductus and prevent the morbidity related to PDA and the complications of surgical ligation.
Interventions
- DRUG indomethacin (two different dosing regimens)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2003-08 |
| Est. Completion | 2006-07 |
| Phase | Phase 2 |
What the finished NCT00187447 record still lists
NCT00187447 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 1 intervention - of which indomethacin (two different dosing regimens) is the first listed.
NCT00187447 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00187447 about?
NCT00187447 is a clinical study titled "Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus". The purpose of this study is to examine if a higher dose of indomethacin will increase the rate of ductus arteriosus closure in extremely premature infants without increasing the side effects. The long term objective is to find the optimal dosing of indomethacin for permanent closure of the Ductus a...
What is the current status of trial NCT00187447?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2003-08. Estimated completion is 2006-07.
What interventions are being tested in trial NCT00187447?
The interventions under investigation include: indomethacin (two different dosing regimens) (DRUG).
Who is sponsoring clinical trial NCT00187447?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00187447's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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