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Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer
NCT00185744 · View on ClinicalTrials.gov ↗
Study Summary
To determine whether an accelerated course of radiotherapy delivered to the lumpectomy cavity plus margin using IORT as a single dose, intracavitary brachytherapy with the MammoSite device over 5 days, partial breast 3-D CRT in 5 days, or stereotactic APBI over 4 days is a feasible and safe alternative to a six and a half week course of whole breast radiotherapy. The study will measure both short and long-term complications of radiation treatment, short and long-term breast cosmesis, local rates of in-breast cancer recurrence, regional recurrences, distant metastases, and overall survival.
Conditions Studied
Interventions
- PROCEDURE Lumpectomy
- RADIATION Intra-Operative Radiotherapy (IORT)
- RADIATION Whole Breast Radiotherapy
- RADIATION Intracavitary Brachytherapy
- RADIATION Accelerated External Beam 3-D Conformal Radiotherapy
Study Locations (1)
California
- Stanford University School of Medicine — Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 121 participants |
| Start Date | 2002-09 |
| Est. Completion | 2029-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00185744
The ClinicalTrials.gov registry entry for NCT00185744 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 121 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Stanford University, which has 1,643 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions — of which Lumpectomy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00185744 reports 1 study location spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00185744 about?
NCT00185744 is a clinical study titled "Accelerated Partial Breast Irradiation Following Lumpectomy for Breast Cancer". To determine whether an accelerated course of radiotherapy delivered to the lumpectomy cavity plus margin using IORT as a single dose, intracavitary brachytherapy with the MammoSite device over 5 days, partial breast 3-D CRT in 5 days, or stereotactic APBI over 4 days is a feasible and safe alternat...
What is the current status of trial NCT00185744?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 121 participants. The study started on 2002-09. Estimated completion is 2029-03.
What conditions does trial NCT00185744 study?
This clinical trial studies the following conditions: Breast Cancer, Carcinoma, Ductal. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00185744?
The interventions under investigation include: Lumpectomy (PROCEDURE), Intra-Operative Radiotherapy (IORT) (RADIATION), Whole Breast Radiotherapy (RADIATION), Intracavitary Brachytherapy (RADIATION), Accelerated External Beam 3-D Conformal Radiotherapy (RADIATION). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00185744?
This trial is sponsored by Stanford University, which has 1,643 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00185744 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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