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NCT00182741 · ClinicalTrials.gov registry record · Phase 2

Calcitriol, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer

A Phase 2 study, sponsored by OHSU Knight Cancer Institute.

Completed
Registry status
Phase 2
Development phase
19
Enrollment target

NCT00182741: Completed Phase 2 study, sponsored by OHSU Knight Cancer Institute.

NCT00182741 is a Phase 2 study that has completed, run by OHSU Knight Cancer Institute. The registered enrollment target is 19 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00182741, a Phase 2 study, has completed, sponsored by OHSU Knight Cancer Institute.

COMPLETED
Registry status
Phase 2
Development phase
19 participants
Enrollment target

Study Summary

RATIONALE: Calcitriol may cause prostate cancer cells to look more like normal cells, and to grow and spread more slowly. Drugs used in chemotherapy, such as mitoxantrone and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase II trial is studying how well giving calcitriol together with mitoxantrone and prednisone works in treating patients with metastatic prostate cancer.

Interventions

  • DRUG prednisone
  • DIETARY_SUPPLEMENT calcitriol
  • DRUG mitoxantrone hydrochloride

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2004-09
Est. Completion 2006-08
Phase Phase 2
OHSU Knight Cancer Institute

211 total trials

What the finished NCT00182741 record still lists

NCT00182741 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 3 interventions - of which prednisone is the first listed.

NCT00182741 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00182741 about?

NCT00182741 is a clinical study titled "Calcitriol, Mitoxantrone, and Prednisone in Treating Patients With Metastatic Prostate Cancer". RATIONALE: Calcitriol may cause prostate cancer cells to look more like normal cells, and to grow and spread more slowly. Drugs used in chemotherapy, such as mitoxantrone and prednisone, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from di...

What is the current status of trial NCT00182741?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 19 participants. The study started on 2004-09. Estimated completion is 2006-08.

What interventions are being tested in trial NCT00182741?

The interventions under investigation include: prednisone (DRUG), calcitriol (DIETARY_SUPPLEMENT), mitoxantrone hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00182741?

This trial is sponsored by OHSU Knight Cancer Institute, which has 211 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00182741's enrollment target sits among peer trials

19 1894th of 2000 higher than 103 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00182741, the US trial registry maintained by the National Library of Medicine. NCT00182741 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.