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NCT00182390 · ClinicalTrials.gov registry record · Phase 3
Premature Infants in Need of Transfusion (PINT)
A Phase 3 study, sponsored by McMaster University.
- Completed
- Registry status
- Phase 3
- Development phase
- 424
- Enrollment target
NCT00182390: Completed Phase 3 study, sponsored by McMaster University.
NCT00182390 is a Phase 3 study that has completed, run by McMaster University. The registered enrollment target is 424 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (45% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00182390, a Phase 3 study, has completed, sponsored by McMaster University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 424 participants
- Enrollment target
Study Summary
Hypothesis: That a high hemoglobin threshold for transfusion in extremely low birth weight (ELBW) infants is associated with a lower rate of survival without severe morbidity (defined as one or more of retinopathy of prematurity, bronchopulmonary dysplasia, or periventricular leukomalacia/ventriculomegaly). Primary Objective: To determine whether either a liberal or more restrictive threshold of hemoglobin level for red cell transfusion in ELBW infants is safer, by randomizing to either a high transfusion hemoglobin threshold or a low transfusion hemoglobin threshold. Follow-up at a corrected age of 18 months represents a conventional age at which to first assess neurodevelopmental outcomes, and to predict long-term outcomes.
Interventions
- PROCEDURE Red blood cell transfusion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 424 participants |
| Start Date | 2001-02 |
| Est. Completion | 2005-11 |
| Phase | Phase 3 |
What the finished NCT00182390 record still lists
NCT00182390 is an interventional study that assigns participants to a tested intervention. The registered 424 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (45% lower).
The record links to 0 conditions, and to 1 intervention - of which Red blood cell transfusion is the first listed.
NCT00182390 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00182390 about?
NCT00182390 is a clinical study titled "Premature Infants in Need of Transfusion (PINT)". Hypothesis: That a high hemoglobin threshold for transfusion in extremely low birth weight (ELBW) infants is associated with a lower rate of survival without severe morbidity (defined as one or more of retinopathy of prematurity, bronchopulmonary dysplasia, or periventricular leukomalacia/ventriculo...
What is the current status of trial NCT00182390?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 424 participants. The study started on 2001-02. Estimated completion is 2005-11.
What interventions are being tested in trial NCT00182390?
The interventions under investigation include: Red blood cell transfusion (PROCEDURE).
Who is sponsoring clinical trial NCT00182390?
This trial is sponsored by McMaster University, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00182390's enrollment target sits among peer trials
424 884th of 2000 higher than 1,116 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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