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NCT00181896 · ClinicalTrials.gov registry record · Phase 4
Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder
A Phase 4 study, sponsored by Massachusetts General Hospital.
- Terminated
- Registry status
- Phase 4
- Development phase
- 1
- Enrollment target
NCT00181896: Clinical Trial Phase 4 study, sponsored by Massachusetts General Hospital.
NCT00181896 is a Phase 4 study that was terminated before completion, run by Massachusetts General Hospital. The registered enrollment target is 1 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00181896, a Phase 4 study, was terminated before completion, sponsored by Massachusetts General Hospital.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 1 participants
- Enrollment target
Study Summary
This is an 8-week open label study of bupropion SR in the treatment of youth with bipolar depression with adequate mood stabilization. All youth will be closely monitored for treatment emergent manic activation and drug-drug interactions with ongoing antimanic agents. The main objective of this study is to assess the safety and effectiveness of bupropion SR in the treatment of bipolar depression in children and adolescents.
Interventions
- DRUG bupropion SR
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2005-01 |
| Phase | Phase 4 |
Why NCT00181896 stopped before completion
NCT00181896 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which bupropion SR is the first listed.
NCT00181896 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00181896 about?
NCT00181896 is a clinical study titled "Bupropion SR for Major Depression and Depression NOS in Children and Adolescents With Bipolar Disorder". This is an 8-week open label study of bupropion SR in the treatment of youth with bipolar depression with adequate mood stabilization. All youth will be closely monitored for treatment emergent manic activation and drug-drug interactions with ongoing antimanic agents. The main objective of this stu...
What is the current status of trial NCT00181896?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 1 participants. The study started on 2005-01.
What interventions are being tested in trial NCT00181896?
The interventions under investigation include: bupropion SR (DRUG).
Who is sponsoring clinical trial NCT00181896?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00181896's enrollment target sits among peer trials
1 2000th of 2000 the lowest of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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