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NCT00178490 · ClinicalTrials.gov registry record · Phase 1
Effect of High Blood Pressure and Antihypertensive Treatment on Brain Functioning in Children
A Phase 1 study, sponsored by University of Rochester.
- Completed
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
NCT00178490: Completed Phase 1 study, sponsored by University of Rochester.
NCT00178490 is a Phase 1 study that has completed, run by University of Rochester. The registered enrollment target is 100 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00178490, a Phase 1 study, has completed, sponsored by University of Rochester.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
Study Summary
High blood pressure, or hypertension, affects up to 10% of minority children and adolescents. Although complications of high blood pressure, such as stroke and heart attack, are uncommon in childhood, high blood pressure-related organ damage can occur at a young age. Studies with young adults have indicated that high blood pressure can affect the central nervous system, resulting in deficits in brain function. However, more research is necessary to confirm the association between neurocognitive deficits and high blood pressure in children and to determine if these deficits are reversible with treatment. This study will determine whether high blood pressure in children and adolescents has subtle effects on learning, attention, and concentration. The study will also determine the effect of an antihypertensive treatment plan, involving a combination of diet, weight loss, increased exercise, and if needed, blood pressure medication, on brain function in children and adolescents receiving treatment for high blood pressure.
Interventions
- DRUG High blood pressure treatment
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2005-01 |
| Est. Completion | 2010-01 |
| Phase | Phase 1 |
What the finished NCT00178490 record still lists
NCT00178490 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher).
The record links to 0 conditions, and to 1 intervention - of which High blood pressure treatment is the first listed.
NCT00178490 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00178490 about?
NCT00178490 is a clinical study titled "Effect of High Blood Pressure and Antihypertensive Treatment on Brain Functioning in Children". High blood pressure, or hypertension, affects up to 10% of minority children and adolescents. Although complications of high blood pressure, such as stroke and heart attack, are uncommon in childhood, high blood pressure-related organ damage can occur at a young age. Studies with young adults have i...
What is the current status of trial NCT00178490?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2005-01. Estimated completion is 2010-01.
What interventions are being tested in trial NCT00178490?
The interventions under investigation include: High blood pressure treatment (DRUG).
Who is sponsoring clinical trial NCT00178490?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00178490's enrollment target sits among peer trials
100 546th of 2000 higher than 1,411 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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