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NCT00177801 · ClinicalTrials.gov registry record

Organ Transplant Infection Prevention and Detection Project

A clinical trial, sponsored by University of Pittsburgh.

Completed
Registry status
200
Enrollment target

NCT00177801 is a clinical trial that has completed, run by University of Pittsburgh. The registered enrollment target is 200 participants.

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The verdict

NCT00177801 has completed, sponsored by University of Pittsburgh.

COMPLETED
Registry status
200 participants
Enrollment target

Study Summary

Fungal infections are leading causes of morbidity and mortality in transplant recipients, yet comprehensive epidemiologic studies in this area are lacking. For this reason, the Centers for Disease Control and Prevention have provided a grant to the University of Pittsburgh to study this subject. The study has four specific aims: 1\. To determine the risk of fungal infections in a center where "tolerogenic" immunosuppressive protocols are currently in place, and to determine whether there are any measures of immune system function which correlate with risk of fungal infection. 2: To create a repository of serum, urine and bronchoalveolar lavage specimens for the purpose of determining the effectiveness of novel diagnostic tests for invasive fungal infections. Such a repository could also be utilized for the purpose of determining the effectiveness of novel diagnostic tests for viral infections such as West Nile Virus, cytomegalovirus, HHV-6 and HHV-8. Specific aim 1 will be investigated by creating a prospective database of solid organ transplant recipients at the University of Pittsburgh Medical Center, including demographic factors as well as subsequent development of infection. The immune function of patients will be assessed by measuring T cell subsets and assessing T cell function using the Cylex assay. Specific aim 2 involves collection of serum, urine and bronchoalveolar lavage fluid. These specimens will be stored and later tested at the Centers for Disease Control and Prevention in the assessment of novel tests developed for the diagnosis of invasive fungal infections.

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2006-05
Est. Completion 2012-08

Sponsor

University of Pittsburgh

1,238 total trials

What the Registry Record Tells You About NCT00177801

The ClinicalTrials.gov registry entry for NCT00177801 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00177801 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00177801 about?

NCT00177801 is a clinical study titled "Organ Transplant Infection Prevention and Detection Project". Fungal infections are leading causes of morbidity and mortality in transplant recipients, yet comprehensive epidemiologic studies in this area are lacking. For this reason, the Centers for Disease Control and Prevention have provided a grant to the University of Pittsburgh to study this subject. Th...

What is the current status of trial NCT00177801?

This trial is currently completed. The enrollment target is 200 participants. The study started on 2006-05. Estimated completion is 2012-08.

Who is sponsoring clinical trial NCT00177801?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.