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NCT00177736 · ClinicalTrials.gov registry record

Pharmacodynamic Parameters of Two Different Doses of Cefepime

A clinical trial, sponsored by University of Pittsburgh.

Completed
Registry status
180
Enrollment target

NCT00177736 is a clinical trial that has completed, run by University of Pittsburgh. The registered enrollment target is 180 participants.

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The verdict

NCT00177736 has completed, sponsored by University of Pittsburgh.

COMPLETED
Registry status
180 participants
Enrollment target

Study Summary

Pharmacokinetics is the study of the disposition of drugs in the body, while pharmacodynamics considers the interaction of the drug at the site of infection over time. Mathematical models of antibiotic pharmacodynamics are sometimes used to predict if antibiotic doses are sufficient to treat infection with organisms of different minimal inhibitory concentrations of the antibiotic. Based on these models, there has been speculation that the antibiotic cefepime dosed at one gram every 12 hours, is insufficient to kill all organisms within the "susceptible" range. This study of patients treated with cefepime will involve the collection of blood to determine cefepime concentrations, and determine if those concentrations are effective in killing the bacteria at the site of infection.

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2005-09
Est. Completion 2007-12

Sponsor

University of Pittsburgh

1,238 total trials

What the Registry Record Tells You About NCT00177736

The ClinicalTrials.gov registry entry for NCT00177736 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00177736 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00177736 about?

NCT00177736 is a clinical study titled "Pharmacodynamic Parameters of Two Different Doses of Cefepime". Pharmacokinetics is the study of the disposition of drugs in the body, while pharmacodynamics considers the interaction of the drug at the site of infection over time. Mathematical models of antibiotic pharmacodynamics are sometimes used to predict if antibiotic doses are sufficient to treat infecti...

What is the current status of trial NCT00177736?

This trial is currently completed. The enrollment target is 180 participants. The study started on 2005-09. Estimated completion is 2007-12.

Who is sponsoring clinical trial NCT00177736?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.