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NCT00177333 · ClinicalTrials.gov registry record · Phase 4
Serum Levels of Doxycycline at the Time of Abortion With Two Dosing Regimens
A Phase 4 study of Vomiting and Abortion, Induced, sponsored by University of Pittsburgh.
- Completed
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT00177333: Completed Phase 4 study of Vomiting and Abortion, Induced, sponsored by University of Pittsburgh.
NCT00177333 is a Phase 4 study of Vomiting and Abortion, Induced that has completed, run by University of Pittsburgh. The registered enrollment target is 40 participants, below the 102-participant average among 9 other Vomiting trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00177333, a Phase 4 study of Vomiting and Abortion, Induced, has completed, sponsored by University of Pittsburgh.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized double-blind, controlled trial comparing two regimens of pre-abortion doxycycline. The aims of the study are to determine the serum levels of doxycycline when administered pre-operatively 4 hours or approximately 18 hours before a dilation and evacuation (D \& E) abortion. The hypotheses being tested are that subjects who receive doxycycline with food the night before an abortion will have adequate serum levels, but less nausea and vomiting compared to women who take the doxycycline on an empty stomach on the morning of the abortion. Subjects will either take 200mg doxycycline on the night before and 2 caps placebo with a sip of water on the morning of surgery or 2 caps placebo the night before and 200mg doxycycline on the morning of surgery with a sip of water. All capsules will look identical. Diaries, questionnaires and a 10cc sample of blood for doxycycline levels will be collected from the subjects at the time of surgery.
Conditions Studied
Interventions
- DRUG Doxycycline
Study Locations (1)
Pennsylvania
- Magee-Womens Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2005-09 |
| Est. Completion | 2006-05 |
| Phase | Phase 4 |
What the finished NCT00177333 record still lists
NCT00177333 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 102-participant average among 9 other Vomiting trials with a reported enrollment target (61% lower).
The record links to 2 conditions, with Vomiting appearing as the primary indexed condition, and to 1 intervention - of which Doxycycline is the first listed.
NCT00177333 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT00177333 about?
NCT00177333 is a clinical study titled "Serum Levels of Doxycycline at the Time of Abortion With Two Dosing Regimens". This is a randomized double-blind, controlled trial comparing two regimens of pre-abortion doxycycline. The aims of the study are to determine the serum levels of doxycycline when administered pre-operatively 4 hours or approximately 18 hours before a dilation and evacuation (D \& E) abortion. The h...
What is the current status of trial NCT00177333?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2005-09. Estimated completion is 2006-05.
What conditions does trial NCT00177333 study?
This clinical trial studies the following conditions: Vomiting, Abortion, Induced.
What interventions are being tested in trial NCT00177333?
The interventions under investigation include: Doxycycline (DRUG).
Who is sponsoring clinical trial NCT00177333?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00177333 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00177333's enrollment target sits among peer trials
40 7th of 9 higher than 3 of 9 other Vomiting trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Vomiting trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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