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NCT00176241 · ClinicalTrials.gov registry record · Phase 1
Phase I Trial of Biweekly Gemcitabine & Paclitaxel & Low-Dose Radiation for Metastatic or Recurrent Head & Neck Cancer
A Phase 1 study, sponsored by Susanne Arnold.
- Terminated
- Registry status
- Phase 1
- Development phase
- 7
- Enrollment target
NCT00176241: Clinical Trial Phase 1 study, sponsored by Susanne Arnold.
NCT00176241 is a Phase 1 study that was terminated before completion, run by Susanne Arnold. The registered enrollment target is 7 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00176241, a Phase 1 study, was terminated before completion, sponsored by Susanne Arnold.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 7 participants
- Enrollment target
Study Summary
This study seeks to establish the safety of gemcitabine, paclitaxel and low-dose radiation in recurrent, metastatic head and neck cancer through a two-stage dose escalation study, first with Gemcitabine dose escalation and then with low-dose radiation escalation. Treatment Schedule Treatment will be administered on an inpatient or outpatient basis. * Gemcitabine:2000 to 3000mg/m2 IV (in the vein) on days 1 and 15 every 28 days over 30-60 minutes. * Paclitaxel: 150 mg/m2 IV(in the vein)on days 1 and 15 every 28 days over 60 minutes. * Low Dose Radiation: 50-80 cGy twice daily on days 1, 2, 15, \& 16 every 28 days at least 4 hours apart.
Interventions
- DRUG paclitaxel
- DRUG gemcitabine
- RADIATION radiation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2005-12 |
| Est. Completion | 2008-11 |
| Phase | Phase 1 |
Why NCT00176241 stopped before completion
NCT00176241 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 7 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (88% lower).
The record links to 0 conditions, and to 3 interventions - of which paclitaxel is the first listed.
NCT00176241 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00176241 about?
NCT00176241 is a clinical study titled "Phase I Trial of Biweekly Gemcitabine & Paclitaxel & Low-Dose Radiation for Metastatic or Recurrent Head & Neck Cancer". This study seeks to establish the safety of gemcitabine, paclitaxel and low-dose radiation in recurrent, metastatic head and neck cancer through a two-stage dose escalation study, first with Gemcitabine dose escalation and then with low-dose radiation escalation. Treatment Schedule Treatment will ...
What is the current status of trial NCT00176241?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2005-12. Estimated completion is 2008-11.
What interventions are being tested in trial NCT00176241?
The interventions under investigation include: paclitaxel (DRUG), gemcitabine (DRUG), radiation (RADIATION).
Who is sponsoring clinical trial NCT00176241?
This trial is sponsored by Susanne Arnold, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00176241's enrollment target sits among peer trials
7 1972nd of 2000 higher than 27 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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