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NCT00166127 · ClinicalTrials.gov registry record · Phase 3
Study of Blood Concentrations and Physiologic Effects of Levosimendan Given During Heart Surgery
A Phase 3 study, sponsored by Emory University.
- Terminated
- Registry status
- Phase 3
- Development phase
- 1
- Enrollment target
NCT00166127: Clinical Trial Phase 3 study, sponsored by Emory University.
NCT00166127 is a Phase 3 study that was terminated before completion, run by Emory University. The registered enrollment target is 1 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00166127, a Phase 3 study, was terminated before completion, sponsored by Emory University.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 1 participants
- Enrollment target
Study Summary
The purpose of this study protocol is to evaluate the blood concentrations of levosimendan when administered at different doses clinically employed during cardiopulmonary bypass or cardiac manipulation during off pump surgery in patients who require the drug for inotropic support (improved heart function) and the associated hemodynamic variables (vital signs). Levosimendan is one of the first agents in a new class of drugs used to treat heart failure and works via a unique mechanism called calcium sensitization, that makes the heart beat more efficiently. Levosimendan also has unique effects on the blood vessels, as well as causing relaxation, an important therapeutic approach of heart failure therapy.
Interventions
- DRUG Levosimendan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2005-05 |
| Est. Completion | 2007-01 |
| Phase | Phase 3 |
Why NCT00166127 stopped before completion
NCT00166127 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 1 intervention - of which Levosimendan is the first listed.
NCT00166127 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00166127 about?
NCT00166127 is a clinical study titled "Study of Blood Concentrations and Physiologic Effects of Levosimendan Given During Heart Surgery". The purpose of this study protocol is to evaluate the blood concentrations of levosimendan when administered at different doses clinically employed during cardiopulmonary bypass or cardiac manipulation during off pump surgery in patients who require the drug for inotropic support (improved heart fun...
What is the current status of trial NCT00166127?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 1 participants. The study started on 2005-05. Estimated completion is 2007-01.
What interventions are being tested in trial NCT00166127?
The interventions under investigation include: Levosimendan (DRUG).
Who is sponsoring clinical trial NCT00166127?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00166127's enrollment target sits among peer trials
1 2001st of 2000 the lowest of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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