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NCT00166114 · ClinicalTrials.gov registry record · Phase 4
Depression, Epinephrine, and Platelet Function
A Phase 4 study, sponsored by Emory University.
- Completed
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
NCT00166114: Completed Phase 4 study, sponsored by Emory University.
NCT00166114 is a Phase 4 study that has completed, run by Emory University. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00166114, a Phase 4 study, has completed, sponsored by Emory University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
Study Summary
Men and women who have suffered sexual and/or physical abuse before the age of 12 are at increased risk for anxiety and mood disorders, other serious psychiatric disorders, and likely medical illnesses. What is not known is whether adult survivors of childhood adversity experience heightened negative emotions and increased physical responses due to altered norepinephrine or serotonin systems in their brains and bodies. The investigators expect to see that survivors of childhood adversity experience heightened negative emotions and increased physical responses to stress.
Primary Outcome
Number of subjects that showed no response, partial response, and response based on scores from baseline and week 8. The 21-item HDRS measures depression severity. The scoring is sum the total of all 21 items to arrive at the total score, with a range of 0 to 60, where higher scores indicated greater severity. Nine items are scored on a 5-point scale, ranging from 0 = not present to 4 = severe. Eleven items are scored from 0 - 2 (0 = absent and 2 = severe). The last item is scored on a 4-point
Interventions
- DRUG Escitalopram
- DRUG Desipramine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2002-02 |
| Est. Completion | 2009-01 |
| Phase | Phase 4 |
What the finished NCT00166114 record still lists
NCT00166114 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 2 interventions - of which Escitalopram is the first listed.
NCT00166114 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00166114 about?
NCT00166114 is a clinical study titled "Depression, Epinephrine, and Platelet Function". Men and women who have suffered sexual and/or physical abuse before the age of 12 are at increased risk for anxiety and mood disorders, other serious psychiatric disorders, and likely medical illnesses. What is not known is whether adult survivors of childhood adversity experience heightened negativ...
What is the current status of trial NCT00166114?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2002-02. Estimated completion is 2009-01.
What interventions are being tested in trial NCT00166114?
The interventions under investigation include: Escitalopram (DRUG), Desipramine (DRUG).
Who is sponsoring clinical trial NCT00166114?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00166114's enrollment target sits among peer trials
40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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