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NCT00156715 · ClinicalTrials.gov registry record · Phase 4

Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder

A Phase 4 study, sponsored by Dartmouth-Hitchcock Medical Center.

Completed
Registry status
Phase 4
Development phase
23
Enrollment target

NCT00156715: Completed Phase 4 study, sponsored by Dartmouth-Hitchcock Medical Center.

NCT00156715 is a Phase 4 study that has completed, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 23 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00156715, a Phase 4 study, has completed, sponsored by Dartmouth-Hitchcock Medical Center.

COMPLETED
Registry status
Phase 4
Development phase
23 participants
Enrollment target

Study Summary

The purpose of this study is to examine the efficacy of quetiapine (Seroquel) in reducing substance use in persons diagnosed with schizophrenia. The primary hypothesis is that quetiapine treatment will be associated with a decrease in substance use.

Primary Outcome

Timeline Follow-back (TLFB) procedure was used at screening and baseline to establish current substance use, and it was also used weekly during the course of the study to assess continued alcohol and other substance use. TLFB cosisted of using a calendar and sasking participants to report alcohol and other drug use since last visit. At the screening visit, the TLFB was done for the four weeks prior to the visit.

Interventions

  • DRUG Quetiapine

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2004-03
Est. Completion 2008-10
Phase Phase 4
Dartmouth-Hitchcock Medical Center

427 total trials

What the finished NCT00156715 record still lists

NCT00156715 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which Quetiapine is the first listed.

NCT00156715 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00156715 about?

NCT00156715 is a clinical study titled "Efficacy of Quetiapine in the Treatment of Patients With Schizophrenia and a Comorbid Substance Use Disorder". The purpose of this study is to examine the efficacy of quetiapine (Seroquel) in reducing substance use in persons diagnosed with schizophrenia. The primary hypothesis is that quetiapine treatment will be associated with a decrease in substance use.

What is the current status of trial NCT00156715?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 23 participants. The study started on 2004-03. Estimated completion is 2008-10.

What interventions are being tested in trial NCT00156715?

The interventions under investigation include: Quetiapine (DRUG).

Who is sponsoring clinical trial NCT00156715?

This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00156715's enrollment target sits among peer trials

23 1725th of 2000 higher than 270 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00156715, the US trial registry maintained by the National Library of Medicine. NCT00156715 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.