Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 3

The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome

NCT00143598 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine whether elastic compression stockings used for 2 years are effective in preventing the post-thrombotic syndrome in patients with symptomatic proximal deep venous thrombosis.

Conditions Studied

Interventions

  • DEVICE Knee-length, graduated elastic compression stocking
  • DEVICE Knee-length, placebo stocking

Study Locations (20)

Ontario

  • Hamilton Health Sciences - General Hospital — Hamilton
  • Hamilton Health Sciences - Chedoke Division — Hamilton
  • Hamilton Health Sciences - McMaster University Medical Centre — Hamilton
  • St. Joseph's Healthcare Hamilton — Hamilton
  • Hamilton Health Sciences - Henderson General Hospital — Hamilton
  • London Health Sciences Centre — London
  • The Ottawa Hospital, Civic Campus — Ottawa
  • Sunnybrook & Women's College Health Sciences Centre — Toronto
  • University Health Network - Toronto General Hospital — Toronto

Quebec

  • Centre Hospitalier Pierre-Boucher — Longueuil
  • Hôpital Maisonneuve-Rosemont — Montreal
  • Centre Hospitalier de l'Université de Montréal - Hôpital Notre-Dame — Montreal
  • Centre Hospitalier de l'Université de Montréal - Hôpital Hôtel-Dieu — Montreal
  • Royal Victoria Hospital - McGill University Health Centre — Montreal

Michigan

  • Henry Ford Health Systerm — Detroit

North Carolina

  • Duke University Medical Center — Durham

Oklahoma

  • Oklahoma University Health Sciences Center — Oklahoma City

British Columbia

  • Victoria Heart Institute Foundation — Victoria

Manitoba

  • St. Boniface General Hospital — Winnipeg

Nova Scotia

  • QE II Health Sciences Centre — Halifax

Trial Details

FieldValue
Enrollment Target 806 participants
Start Date 2004-06
Est. Completion 2012-02
Phase Phase 3

Interested in This Trial?

Always speak with your doctor before enrolling in a clinical trial.

Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00143598

The ClinicalTrials.gov registry entry for NCT00143598 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 806 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sir Mortimer B. Davis - Jewish General Hospital, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Deep Venous Thrombosis appearing as the primary indexed condition, and to 2 interventions — of which Knee-length, graduated elastic compression stocking is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00143598 reports 20 study locations spanning 8 distinct geographic areas — top geographies include Ontario, Quebec, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00143598 about?

NCT00143598 is a clinical study titled "The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome". The purpose of this study is to determine whether elastic compression stockings used for 2 years are effective in preventing the post-thrombotic syndrome in patients with symptomatic proximal deep venous thrombosis.

What is the current status of trial NCT00143598?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 806 participants. The study started on 2004-06. Estimated completion is 2012-02.

What conditions does trial NCT00143598 study?

This clinical trial studies the following conditions: Deep Venous Thrombosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00143598?

The interventions under investigation include: Knee-length, graduated elastic compression stocking (DEVICE), Knee-length, placebo stocking (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00143598?

This trial is sponsored by Sir Mortimer B. Davis - Jewish General Hospital, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00143598 being conducted?

This trial has 20 study locations across Michigan, North Carolina, Oklahoma, British Columbia, Manitoba. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial