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NCT00140998 · ClinicalTrials.gov registry record · Phase 3

Estrogen Treatment (Oral vs. Patches) in Turner Syndrome

A Phase 3 study, sponsored by Nemours Children's Clinic.

Completed
Registry status
Phase 3
Development phase
16
Enrollment target

NCT00140998: Completed Phase 3 study, sponsored by Nemours Children's Clinic.

NCT00140998 is a Phase 3 study that has completed, run by Nemours Children's Clinic. The registered enrollment target is 16 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00140998, a Phase 3 study, has completed, sponsored by Nemours Children's Clinic.

COMPLETED
Registry status
Phase 3
Development phase
16 participants
Enrollment target

Study Summary

The study attempts to evaluate if the way of administering estrogen, the principal female hormone, via patches or orally, affects the way estrogen works in girls with Turner Syndrome. These are girls who are very short and whose ovaries do not work. We will examine changes bone, protein and fat metabolism under the influence of estrogen delivered by a patch trough the skin vs estrogen taken orally. These studies are conducted while the girls are taking GH therapy.

Interventions

  • DRUG 17 beta estradiol

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2001-01
Est. Completion 2004-06
Phase Phase 3
Nemours Children's Clinic

108 total trials

What the finished NCT00140998 record still lists

NCT00140998 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which 17 beta estradiol is the first listed.

NCT00140998 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00140998 about?

NCT00140998 is a clinical study titled "Estrogen Treatment (Oral vs. Patches) in Turner Syndrome". The study attempts to evaluate if the way of administering estrogen, the principal female hormone, via patches or orally, affects the way estrogen works in girls with Turner Syndrome. These are girls who are very short and whose ovaries do not work. We will examine changes bone, protein and fat meta...

What is the current status of trial NCT00140998?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 16 participants. The study started on 2001-01. Estimated completion is 2004-06.

What interventions are being tested in trial NCT00140998?

The interventions under investigation include: 17 beta estradiol (DRUG).

Who is sponsoring clinical trial NCT00140998?

This trial is sponsored by Nemours Children's Clinic, which has 108 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00140998's enrollment target sits among peer trials

16 1974th of 2000 higher than 24 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00140998, the US trial registry maintained by the National Library of Medicine. NCT00140998 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.