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NCT00138840 · ClinicalTrials.gov registry record · Phase 2
Study of STA-5326 Mesylate in Patients With Moderate to Severe Crohn's Disease
A Phase 2 study, sponsored by Synta Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 282
- Enrollment target
NCT00138840: Completed Phase 2 study, sponsored by Synta Pharmaceuticals.
NCT00138840 is a Phase 2 study that has completed, run by Synta Pharmaceuticals. The registered enrollment target is 282 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (112% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00138840, a Phase 2 study, has completed, sponsored by Synta Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 282 participants
- Enrollment target
Study Summary
STA-5326 is an experimental drug that has been shown to block the release of interleukin-12 from peripheral blood mononuclear cells. Given this activity on the immune system, STA-5326 mesylate is a potential treatment for various autoimmune diseases, such as Crohn's disease, that are mediated by the inappropriate expression of Th1 cytokines. This study is evaluating the use of STA-5326 mesylate in patients with moderate to severe, active Crohn's disease. Study visits include a screening visit, 9 treatment period visits over 6 months and a follow-up visit that will occur 30 days following the end of treatment. Study drug treatment will continue for up to 6 months.
Interventions
- DRUG STA-5326 mesylate
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 282 participants |
| Start Date | 2005-08 |
| Phase | Phase 2 |
What the finished NCT00138840 record still lists
NCT00138840 is an interventional study that assigns participants to a tested intervention. The registered 282 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (112% higher).
The record links to 0 conditions, and to 1 intervention - of which STA-5326 mesylate is the first listed.
NCT00138840 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00138840 about?
NCT00138840 is a clinical study titled "Study of STA-5326 Mesylate in Patients With Moderate to Severe Crohn's Disease". STA-5326 is an experimental drug that has been shown to block the release of interleukin-12 from peripheral blood mononuclear cells. Given this activity on the immune system, STA-5326 mesylate is a potential treatment for various autoimmune diseases, such as Crohn's disease, that are mediated by the...
What is the current status of trial NCT00138840?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 282 participants. The study started on 2005-08.
What interventions are being tested in trial NCT00138840?
The interventions under investigation include: STA-5326 mesylate (DRUG).
Who is sponsoring clinical trial NCT00138840?
This trial is sponsored by Synta Pharmaceuticals, which has 21 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00138840's enrollment target sits among peer trials
282 195th of 2000 higher than 1,805 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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