Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00137306 · ClinicalTrials.gov registry record · Phase 4

Facilitating the Adoption of Evidence-Based Depression Management in Substance Use Treatment Programs

A Phase 4 study, sponsored by US Department of Veterans Affairs.

Completed
Registry status
Phase 4
Development phase
300
Enrollment target

NCT00137306: Completed Phase 4 study, sponsored by US Department of Veterans Affairs.

NCT00137306 is a Phase 4 study that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 300 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (42% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00137306, a Phase 4 study, has completed, sponsored by US Department of Veterans Affairs.

COMPLETED
Registry status
Phase 4
Development phase
300 participants
Enrollment target

Study Summary

Comorbid depression has been consistently linked to worse outcomes for patients in substance abuse treatment programs. Practice guidelines recommend pharmacotherapy for comorbid depression if symptoms persist after a 4-week "wash-out" period for detoxification (e.g., Veterans Health Administration; American Psychiatric Association). Medications may be considered earlier if a patient has current symptoms and a history of major depressive disorder (MDD) during periods of sobriety. Current efficacy data suggest that antidepressant medication can improve both depression and substance use outcomes among comorbid patients Guideline-concordant use of antidepressant medication for persons with comorbid substance use and depressive disorders, however, is not routine in many VA substance abuse treatment settings.

Interventions

  • PROCEDURE Facilitate evidence-based treatment for depression

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2004-01
Est. Completion 2006-10
Phase Phase 4
US Department of Veterans Affairs

632 total trials

What the finished NCT00137306 record still lists

NCT00137306 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (42% lower).

The record links to 0 conditions, and to 1 intervention - of which Facilitate evidence-based treatment for depression is the first listed.

NCT00137306 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00137306 about?

NCT00137306 is a clinical study titled "Facilitating the Adoption of Evidence-Based Depression Management in Substance Use Treatment Programs". Comorbid depression has been consistently linked to worse outcomes for patients in substance abuse treatment programs. Practice guidelines recommend pharmacotherapy for comorbid depression if symptoms persist after a 4-week "wash-out" period for detoxification (e.g., Veterans Health Administration; ...

What is the current status of trial NCT00137306?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 300 participants. The study started on 2004-01. Estimated completion is 2006-10.

What interventions are being tested in trial NCT00137306?

The interventions under investigation include: Facilitate evidence-based treatment for depression (PROCEDURE).

Who is sponsoring clinical trial NCT00137306?

This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00137306's enrollment target sits among peer trials

300 269th of 2000 higher than 1,709 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00353483 · 300 participants

    Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells

  • NCT00588185 · 300 participants · NA

    [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer

  • NCT00682032 · 300 participants · NA

    The Effect of Beta-glucan in Non-Small Cell Lung Cancer

  • NCT00870064 · 300 participants · NA

    The Treatment of Type I Open Fractures in Pediatrics

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00137306, the US trial registry maintained by the National Library of Medicine. NCT00137306 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.