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NCT00136747 · ClinicalTrials.gov registry record · Phase 1
The Effects of Memantine and Bupropion on Acute, Reinforcing, and Conditioned Effects of Cigarettes - 1
A Phase 1 study, sponsored by New York State Psychiatric Institute.
- Completed
- Registry status
- Phase 1
- Development phase
- 45
- Enrollment target
NCT00136747 is a Phase 1 study that has completed, run by New York State Psychiatric Institute. The registered enrollment target is 45 participants.
The verdict
NCT00136747, a Phase 1 study, has completed, sponsored by New York State Psychiatric Institute.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 45 participants
- Enrollment target
Study Summary
One of nicotine's effects on the body is at the level of the NMDA receptors in the brain. Memantine is a drug that also affects NMDA receptors, making it a candidate for the treatment of nicotine addiction. The purpose of this study is to evaluate the effectiveness of memantine using a laboratory model of tobacco addiction. The investigators will compare the effects of memantine with bupropion, medication currently used to facilitate smoking cessation.
Interventions
- DRUG placebo
- DRUG Memantine
- DRUG bupropion
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2004-01 |
| Est. Completion | 2009-05 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00136747
The ClinicalTrials.gov registry entry for NCT00136747 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is New York State Psychiatric Institute, which has 364 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.
NCT00136747 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00136747 about?
NCT00136747 is a clinical study titled "The Effects of Memantine and Bupropion on Acute, Reinforcing, and Conditioned Effects of Cigarettes - 1". One of nicotine's effects on the body is at the level of the NMDA receptors in the brain. Memantine is a drug that also affects NMDA receptors, making it a candidate for the treatment of nicotine addiction. The purpose of this study is to evaluate the effectiveness of memantine using a laboratory mo...
What is the current status of trial NCT00136747?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 45 participants. The study started on 2004-01. Estimated completion is 2009-05.
What interventions are being tested in trial NCT00136747?
The interventions under investigation include: placebo (DRUG), Memantine (DRUG), bupropion (DRUG).
Who is sponsoring clinical trial NCT00136747?
This trial is sponsored by New York State Psychiatric Institute, which has 364 total clinical trials registered on ClinicalTrials.gov.
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