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NCT00135369 · ClinicalTrials.gov registry record · Phase 3

Switching HIV-1 Infected Subjects From a Highly Active Anti-Retroviral Treatment (HAART) Regimen Dosed Twice Daily or More Frequently to a Once-Daily Regimen

A Phase 3 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 3
Development phase
300
Enrollment target

NCT00135369: Completed Phase 3 study, sponsored by Bristol-Myers Squibb.

NCT00135369 is a Phase 3 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 300 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (61% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00135369, a Phase 3 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 3
Development phase
300 participants
Enrollment target

Study Summary

The purpose of this study is to demonstrate that virologically controlled HIV-infected individuals can successfully switch from a standard-of-care regimen dosed twice-daily or more frequently to a simpler once-daily (QD) regimen while maintaining virologic control, as evaluated by the proportion of subjects who continue to have plasma HIV-1 levels \<50 copies/mL after switching to a QD regimen.

Interventions

  • DRUG stavudine extended-release, lamivudine, efavirenz

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2002-09
Est. Completion 2005-07
Phase Phase 3
Bristol-Myers Squibb

1,025 total trials

What the finished NCT00135369 record still lists

NCT00135369 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (61% lower).

The record links to 0 conditions, and to 1 intervention - of which stavudine extended-release, lamivudine, efavirenz is the first listed.

NCT00135369 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00135369 about?

NCT00135369 is a clinical study titled "Switching HIV-1 Infected Subjects From a Highly Active Anti-Retroviral Treatment (HAART) Regimen Dosed Twice Daily or More Frequently to a Once-Daily Regimen". The purpose of this study is to demonstrate that virologically controlled HIV-infected individuals can successfully switch from a standard-of-care regimen dosed twice-daily or more frequently to a simpler once-daily (QD) regimen while maintaining virologic control, as evaluated by the proportion of ...

What is the current status of trial NCT00135369?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 300 participants. The study started on 2002-09. Estimated completion is 2005-07.

What interventions are being tested in trial NCT00135369?

The interventions under investigation include: stavudine extended-release, lamivudine, efavirenz (DRUG).

Who is sponsoring clinical trial NCT00135369?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00135369's enrollment target sits among peer trials

300 1122nd of 2000 higher than 840 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00135369, the US trial registry maintained by the National Library of Medicine. NCT00135369 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.