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NCT00134667 · ClinicalTrials.gov registry record · Phase 4
Macugen (Pegaptanib Sodium) Alone, Versus Macugen in Combination With PDT (Photodynamic Therapy) With Visudyne (Verteporfin) in Patients With Age-Related Macular Degeneration (AMD)
A Phase 4 study, sponsored by Eyetech Pharmaceuticals.
- Terminated
- Registry status
- Phase 4
- Development phase
- 360
- Enrollment target
NCT00134667: Clinical Trial Phase 4 study, sponsored by Eyetech Pharmaceuticals.
NCT00134667 is a Phase 4 study that was terminated before completion, run by Eyetech Pharmaceuticals. The registered enrollment target is 360 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (31% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00134667, a Phase 4 study, was terminated before completion, sponsored by Eyetech Pharmaceuticals.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 360 participants
- Enrollment target
Study Summary
The purpose of the trial is to compare whether Macugen (pegaptanib sodium) in combination with PDT with Visudyne (verteporfin) is safe and effective in slowing down the leakage of fluid within the eye and thereby stabilizing or improving vision when compared to Macugen alone. Patients must be recently diagnosed with predominantly classic wet AMD and must be eligible for PDT.
Interventions
- DRUG Photodynamic Therapy (PDT) with Visudyne (verteporfin)
- DRUG Macugen (pegaptanib sodium)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 360 participants |
| Start Date | 2005-03 |
| Est. Completion | 2008-10 |
| Phase | Phase 4 |
Why NCT00134667 stopped before completion
NCT00134667 is an interventional study that assigns participants to a tested intervention. The registered 360 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (31% lower).
The record links to 0 conditions, and to 2 interventions - of which Photodynamic Therapy (PDT) with Visudyne (verteporfin) is the first listed.
NCT00134667 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00134667 about?
NCT00134667 is a clinical study titled "Macugen (Pegaptanib Sodium) Alone, Versus Macugen in Combination With PDT (Photodynamic Therapy) With Visudyne (Verteporfin) in Patients With Age-Related Macular Degeneration (AMD)". The purpose of the trial is to compare whether Macugen (pegaptanib sodium) in combination with PDT with Visudyne (verteporfin) is safe and effective in slowing down the leakage of fluid within the eye and thereby stabilizing or improving vision when compared to Macugen alone. Patients must be recent...
What is the current status of trial NCT00134667?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 360 participants. The study started on 2005-03. Estimated completion is 2008-10.
What interventions are being tested in trial NCT00134667?
The interventions under investigation include: Photodynamic Therapy (PDT) with Visudyne (verteporfin) (DRUG), Macugen (pegaptanib sodium) (DRUG).
Who is sponsoring clinical trial NCT00134667?
This trial is sponsored by Eyetech Pharmaceuticals, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00134667's enrollment target sits among peer trials
360 225th of 2000 higher than 1,775 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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