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NCT00134381 · ClinicalTrials.gov registry record · Phase 2

Green Tea and Ultraviolet Light-induced Skin Damage

A Phase 2 study, sponsored by Rutgers, The State University of New Jersey.

Terminated
Registry status
Phase 2
Development phase
68
Enrollment target

NCT00134381: Clinical Trial Phase 2 study, sponsored by Rutgers, The State University of New Jersey.

NCT00134381 is a Phase 2 study that was terminated before completion, run by Rutgers, The State University of New Jersey. The registered enrollment target is 68 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (49% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00134381, a Phase 2 study, was terminated before completion, sponsored by Rutgers, The State University of New Jersey.

TERMINATED
Registry status
Phase 2
Development phase
68 participants
Enrollment target

Study Summary

The purpose of this study is to investigate whether topically applied constituents of green tea \[caffeine or (-)-epigallocatechin gallate; EGCG\] have a protective effect on skin exposed to ultraviolet light (UV).

Primary Outcome

The mean change in number of active caspase-3+ apoptotic keratinocytes between 0- and 48-hour time points was calculated for skin biopsy samples of subjects who had been exposed to UVB on symmetrical right and left test sites which were then randomized to receive active test substance (EGCG or caffeine) or placebo (vehicle) at sequential time points after UVB exposure.

Interventions

  • DRUG Placebo
  • DRUG Green Tea

Trial Details

FieldValue
Enrollment Target 68 participants
Start Date 2003-05
Est. Completion 2012-11
Phase Phase 2

Why NCT00134381 stopped before completion

NCT00134381 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (49% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00134381 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00134381 about?

NCT00134381 is a clinical study titled "Green Tea and Ultraviolet Light-induced Skin Damage". The purpose of this study is to investigate whether topically applied constituents of green tea \[caffeine or (-)-epigallocatechin gallate; EGCG\] have a protective effect on skin exposed to ultraviolet light (UV).

What is the current status of trial NCT00134381?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 68 participants. The study started on 2003-05. Estimated completion is 2012-11.

What interventions are being tested in trial NCT00134381?

The interventions under investigation include: Placebo (DRUG), Green Tea (DRUG).

Who is sponsoring clinical trial NCT00134381?

This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00134381's enrollment target sits among peer trials

68 967th of 2000 higher than 1,027 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00134381, the US trial registry maintained by the National Library of Medicine. NCT00134381 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.