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NCT00132691 · ClinicalTrials.gov registry record · Phase 4
Multicenter Uveitis Steroid Treatment (MUST) Trial
A Phase 4 study, sponsored by JHSPH Center for Clinical Trials.
- Completed
- Registry status
- Phase 4
- Development phase
- 255
- Enrollment target
NCT00132691: Completed Phase 4 study, sponsored by JHSPH Center for Clinical Trials.
NCT00132691 is a Phase 4 study that has completed, run by JHSPH Center for Clinical Trials. The registered enrollment target is 255 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (51% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00132691, a Phase 4 study, has completed, sponsored by JHSPH Center for Clinical Trials.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 255 participants
- Enrollment target
Study Summary
The purpose of this study is to compare the effectiveness of standardized systemic therapy versus fluocinolone acetonide implant therapy for the treatment of severe cases of non-infectious intermediate uveitis, posterior uveitis, or panuveitis.
Primary Outcome
Best-corrected visual acuity was measured as the number of letters read from standard logarithmic visual acuity charts by study-certified examiners who were masked to treatment. Visual acuity was measured at all study visits. The primary outcome was eye-specific change in visual acuity from baseline to 2-year follow-up. Positive change values indicate improved vision while negative change values indicate vision has gotten worse. A change of 7.5 letters is considered clinically meaningful.
Interventions
- DRUG fluocinolone acetonide intraocular implant
- DRUG oral corticosteroid with immunosuppressive agents as needed
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 255 participants |
| Start Date | 2005-09 |
| Est. Completion | 2010-12 |
| Phase | Phase 4 |
What the finished NCT00132691 record still lists
NCT00132691 is an interventional study that assigns participants to a tested intervention. The registered 255 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (51% lower).
The record links to 0 conditions, and to 2 interventions - of which fluocinolone acetonide intraocular implant is the first listed.
NCT00132691 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00132691 about?
NCT00132691 is a clinical study titled "Multicenter Uveitis Steroid Treatment (MUST) Trial". The purpose of this study is to compare the effectiveness of standardized systemic therapy versus fluocinolone acetonide implant therapy for the treatment of severe cases of non-infectious intermediate uveitis, posterior uveitis, or panuveitis.
What is the current status of trial NCT00132691?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 255 participants. The study started on 2005-09. Estimated completion is 2010-12.
What interventions are being tested in trial NCT00132691?
The interventions under investigation include: fluocinolone acetonide intraocular implant (DRUG), oral corticosteroid with immunosuppressive agents as needed (DRUG).
Who is sponsoring clinical trial NCT00132691?
This trial is sponsored by JHSPH Center for Clinical Trials, which has 12 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00132691's enrollment target sits among peer trials
255 334th of 2000 higher than 1,664 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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