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NCT00132067 · ClinicalTrials.gov registry record · Phase 2

Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity Cancer

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
60
Enrollment target

NCT00132067: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00132067 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00132067, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
60 participants
Enrollment target

Study Summary

This phase II trial is studying how well vorinostat works in treating patients with recurrent or persistent ovarian epithelial or primary peritoneal cavity cancer. Drugs used in chemotherapy, such as vorinostat, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vorinostat may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Primary Outcome

Time at risk will be assessed from the date of registration onto the study and include all eligible patients who receive any study treatment. An analysis of any potential treatment effect on PFS may be conducted against the historical controls provided in GOG 126 and GOG 146 using a proportional hazards model that includes histological cell type, performance status, and platinum sensitivity.

Interventions

  • DRUG vorinostat

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2005-10
Est. Completion 2008-07
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00132067 record still lists

NCT00132067 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 1 intervention - of which vorinostat is the first listed.

NCT00132067 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00132067 about?

NCT00132067 is a clinical study titled "Vorinostat in Treating Patients With Recurrent or Persistent Ovarian Epithelial or Primary Peritoneal Cavity Cancer". This phase II trial is studying how well vorinostat works in treating patients with recurrent or persistent ovarian epithelial or primary peritoneal cavity cancer. Drugs used in chemotherapy, such as vorinostat, work in different ways to stop the growth of tumor cells, either by killing the cells or...

What is the current status of trial NCT00132067?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2005-10. Estimated completion is 2008-07.

What interventions are being tested in trial NCT00132067?

The interventions under investigation include: vorinostat (DRUG).

Who is sponsoring clinical trial NCT00132067?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00132067's enrollment target sits among peer trials

60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00132067, the US trial registry maintained by the National Library of Medicine. NCT00132067 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.