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NCT00131339 · ClinicalTrials.gov registry record · NA

Augmenting Exposure Therapy With an N-Methyl-D-Aspartate (NMDA) Agonist for Panic Disorder

A NA study, sponsored by Hartford Hospital.

Completed
Registry status
NA
Development phase
40
Enrollment target

NCT00131339: Completed NA study, sponsored by Hartford Hospital.

NCT00131339 is a NA study that has completed, run by Hartford Hospital. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00131339, a NA study, has completed, sponsored by Hartford Hospital.

COMPLETED
Registry status
NA
Development phase
40 participants
Enrollment target

Study Summary

This study involves cognitive behavioral therapy (CBT) and a medication called D-cycloserine (DCS), which is thought to help reduce panic symptoms more effectively by interacting with N-methyl-D-aspartate (NMDA) glutamate receptors, facilitating many forms of learning including the extinction of fear. Participants will be randomly assigned (like flipping a coin) to receive either DCS or a placebo in addition to CBT.

Interventions

  • DRUG D-cycloserine
  • BEHAVIORAL Cognitive behavioral therapy

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2004-11
Est. Completion 2007-03
Phase NA
Hartford Hospital

75 total trials

What the finished NCT00131339 record still lists

NCT00131339 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which D-cycloserine is the first listed.

NCT00131339 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00131339 about?

NCT00131339 is a clinical study titled "Augmenting Exposure Therapy With an N-Methyl-D-Aspartate (NMDA) Agonist for Panic Disorder". This study involves cognitive behavioral therapy (CBT) and a medication called D-cycloserine (DCS), which is thought to help reduce panic symptoms more effectively by interacting with N-methyl-D-aspartate (NMDA) glutamate receptors, facilitating many forms of learning including the extinction of fea...

What is the current status of trial NCT00131339?

This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2004-11. Estimated completion is 2007-03.

What interventions are being tested in trial NCT00131339?

The interventions under investigation include: D-cycloserine (DRUG), Cognitive behavioral therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT00131339?

This trial is sponsored by Hartford Hospital, which has 75 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00131339's enrollment target sits among peer trials

40 1447th of 2000 higher than 465 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00131339, the US trial registry maintained by the National Library of Medicine. NCT00131339 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.