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NCT00130676 · ClinicalTrials.gov registry record · Phase 3
A United States Study of Corlux for Psychotic Symptoms in Psychotic Major Depression
A Phase 3 study, sponsored by Corcept Therapeutics.
- Completed
- Registry status
- Phase 3
- Development phase
- 257
- Enrollment target
NCT00130676 is a Phase 3 study that has completed, run by Corcept Therapeutics. The registered enrollment target is 257 participants.
The verdict
NCT00130676, a Phase 3 study, has completed, sponsored by Corcept Therapeutics.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 257 participants
- Enrollment target
Study Summary
Corlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol. Under normal conditions, cortisol and other hormones are created by the body in response to physical and emotional stress, triggering a healthy stress response. People who suffer from psychotic major depression may have unusually high levels of cortisol circulating within them or abnormal patterns of cortisol levels, overloading the stress response mechanism and causing symptoms of psychosis such as delusional thoughts or hallucinations. If Corlux can keep the body's cortisol receptors from being overloaded, the stress response system may return to normal function, which may result in improvement of symptoms. The purpose of this 56 day study is to learn the safety and effectiveness of Corlux in patients who have been diagnosed with psychotic major depression (PMD).
Interventions
- DRUG Mifepristone
- DRUG matching placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 257 participants |
| Start Date | 2004-09 |
| Est. Completion | 2006-06 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00130676
The ClinicalTrials.gov registry entry for NCT00130676 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 257 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Corcept Therapeutics, which has 54 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Mifepristone is the first listed.
NCT00130676 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00130676 about?
NCT00130676 is a clinical study titled "A United States Study of Corlux for Psychotic Symptoms in Psychotic Major Depression". Corlux (mifepristone) is a new medication that modulates the body's use of a hormone called cortisol. Under normal conditions, cortisol and other hormones are created by the body in response to physical and emotional stress, triggering a healthy stress response. People who suffer from psychotic majo...
What is the current status of trial NCT00130676?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 257 participants. The study started on 2004-09. Estimated completion is 2006-06.
What interventions are being tested in trial NCT00130676?
The interventions under investigation include: Mifepristone (DRUG), matching placebo (DRUG).
Who is sponsoring clinical trial NCT00130676?
This trial is sponsored by Corcept Therapeutics, which has 54 total clinical trials registered on ClinicalTrials.gov.
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