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NCT00130520 · ClinicalTrials.gov registry record · Phase 2

Bevacizumab and Erlotinib Study in Advanced Ovarian Cancer

A Phase 2 study, sponsored by University of Arizona.

Completed
Registry status
Phase 2
Development phase
40
Enrollment target

NCT00130520: Completed Phase 2 study, sponsored by University of Arizona.

NCT00130520 is a Phase 2 study that has completed, run by University of Arizona. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00130520, a Phase 2 study, has completed, sponsored by University of Arizona.

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

The purpose of this project is to determine if a new combination of drugs, erlotinib (Tarceva™) and bevacizumab is safe and effective for treating women diagnosed with ovarian cancer whose cancer has progressed while on prior standard chemotherapy treatment with a taxane (paclitaxel or docetaxel) and a platinum (cisplatin or carboplatin).

Primary Outcome

Objective response was defined using standard RECIST criteria. CR(complete response)= disappearance of all target lesions PR(partial response)=30% decrease in the sum of the longest diameter of target lesions PD(progressive disease)=20% increase in the sum of the longest diameter of target lesions SD(stable disease)= small changes that do not meet above criteria

Interventions

  • DRUG bevacizumab
  • DRUG erlotinib

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2005-06
Est. Completion 2010-05
Phase Phase 2
University of Arizona

349 total trials

What the finished NCT00130520 record still lists

NCT00130520 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 2 interventions - of which bevacizumab is the first listed.

NCT00130520 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00130520 about?

NCT00130520 is a clinical study titled "Bevacizumab and Erlotinib Study in Advanced Ovarian Cancer". The purpose of this project is to determine if a new combination of drugs, erlotinib (Tarceva™) and bevacizumab is safe and effective for treating women diagnosed with ovarian cancer whose cancer has progressed while on prior standard chemotherapy treatment with a taxane (paclitaxel or docetaxel) an...

What is the current status of trial NCT00130520?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2005-06. Estimated completion is 2010-05.

What interventions are being tested in trial NCT00130520?

The interventions under investigation include: bevacizumab (DRUG), erlotinib (DRUG).

Who is sponsoring clinical trial NCT00130520?

This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00130520's enrollment target sits among peer trials

40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00130520, the US trial registry maintained by the National Library of Medicine. NCT00130520 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.