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NCT00124748 · ClinicalTrials.gov registry record · Phase 3

Efficacy of 400 Mg Versus 800 Mg Imatinib in Chronic Myeloid Leukemia in Chronic Phase Patients - TOPS (Tyrosine Kinase Inhibitor Optimization and Selectivity)

A Phase 3 study, sponsored by Novartis Pharmaceuticals.

Terminated
Registry status
Phase 3
Development phase
476
Enrollment target

NCT00124748 is a Phase 3 study that was terminated before completion, run by Novartis Pharmaceuticals. The registered enrollment target is 476 participants.

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The verdict

NCT00124748, a Phase 3 study, was terminated before completion, sponsored by Novartis Pharmaceuticals.

TERMINATED
Registry status
Phase 3
Development phase
476 participants
Enrollment target

Study Summary

This study investigated the safety and efficacy of 400mg Versus 800mg imatinib in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase (CML-CP) using molecular endpoints.

Interventions

  • DRUG Imatinib mesylate

Trial Details

FieldValue
Enrollment Target 476 participants
Start Date 2005-06
Est. Completion 2010-11
Phase Phase 3

Sponsor

Novartis Pharmaceuticals

1,375 total trials

What the Registry Record Tells You About NCT00124748

The ClinicalTrials.gov registry entry for NCT00124748 describes a study currently listed as terminated, categorized as Phase 3. The registered enrollment target is 476 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 1,375 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Imatinib mesylate is the first listed.

NCT00124748 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00124748 about?

NCT00124748 is a clinical study titled "Efficacy of 400 Mg Versus 800 Mg Imatinib in Chronic Myeloid Leukemia in Chronic Phase Patients - TOPS (Tyrosine Kinase Inhibitor Optimization and Selectivity)". This study investigated the safety and efficacy of 400mg Versus 800mg imatinib in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase (CML-CP) using molecular endpoints.

What is the current status of trial NCT00124748?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 476 participants. The study started on 2005-06. Estimated completion is 2010-11.

What interventions are being tested in trial NCT00124748?

The interventions under investigation include: Imatinib mesylate (DRUG).

Who is sponsoring clinical trial NCT00124748?

This trial is sponsored by Novartis Pharmaceuticals, which has 1,375 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.