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NCT00115336 · ClinicalTrials.gov registry record · Phase 4
Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease
A Phase 4 study, sponsored by Children's Hospital Medical Center, Cincinnati.
- Terminated
- Registry status
- Phase 4
- Development phase
- 10
- Enrollment target
NCT00115336: Clinical Trial Phase 4 study, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT00115336 is a Phase 4 study that was terminated before completion, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 10 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00115336, a Phase 4 study, was terminated before completion, sponsored by Children's Hospital Medical Center, Cincinnati.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 10 participants
- Enrollment target
Study Summary
The purpose of this study is to compare ketorolac, a potent, non-steroidal anti-inflammatory drug (NSAID), with ibuprofen, a commonly used NSAID, for the treatment of the painful crisis of sickle cell disease (SCD).
Primary Outcome
The primary endpoint is the time to a 50% reduction in reported pain intensity. This endpoint is relative to the baseline pain intensity rating on the Oucher scale (minimum 0, maximum 10; higher scores indicate greater pain). The endpoint will be reached when the reported pain intensity is at least one-half of the baseline value on two consecutive measurements at least 4 hours apart. The time ascribed to the endpoint will be the time of the second of these two consecutive pain scales. Participan
Interventions
- DRUG Ibuprofen
- DRUG Intravenous Ketorolac
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2005-01 |
| Est. Completion | 2008-12 |
| Phase | Phase 4 |
Why NCT00115336 stopped before completion
NCT00115336 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Ibuprofen is the first listed.
NCT00115336 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00115336 about?
NCT00115336 is a clinical study titled "Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease". The purpose of this study is to compare ketorolac, a potent, non-steroidal anti-inflammatory drug (NSAID), with ibuprofen, a commonly used NSAID, for the treatment of the painful crisis of sickle cell disease (SCD).
What is the current status of trial NCT00115336?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 10 participants. The study started on 2005-01. Estimated completion is 2008-12.
What interventions are being tested in trial NCT00115336?
The interventions under investigation include: Ibuprofen (DRUG), Intravenous Ketorolac (DRUG).
Who is sponsoring clinical trial NCT00115336?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00115336's enrollment target sits among peer trials
10 1940th of 2000 higher than 33 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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