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NCT00113100 · ClinicalTrials.gov registry record · NA

Mechanisms of Skin Repair by Topical Estrogen

A NA study, sponsored by University of Michigan.

Completed
Registry status
NA
Development phase
152
Enrollment target

NCT00113100: Completed NA study, sponsored by University of Michigan.

NCT00113100 is a NA study that has completed, run by University of Michigan. The registered enrollment target is 152 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00113100, a NA study, has completed, sponsored by University of Michigan.

COMPLETED
Registry status
NA
Development phase
152 participants
Enrollment target

Study Summary

The purpose of this study is to investigate the way by which estrogen improves the appearance of sun damaged human skin. Accumulating evidence suggests that estrogen, taken by post menopausal women, may cause skin to look younger as a consequence of reduced wrinkles. Collagen is the most abundant protein in human skin and gives skin its strength and shape. Recent data indicate that short-term topical estrogen (17-beta estradiol) treatment increases collagen production in sun damaged skin. This study will compare the molecular and microscopic effects from topical 17-beta estradiol (E2) when applied to the skin for a short-term duration. It is anticipated that the new knowledge from this study will enable development of new ways to improve the function of aged skin.

Interventions

  • DRUG Topical 17-beta estradiol in ethanol/propylene glycol (ETOH/PG)

Trial Details

FieldValue
Enrollment Target 152 participants
Start Date 2004-08
Est. Completion 2007-06
Phase NA
University of Michigan

1,327 total trials

What the finished NCT00113100 record still lists

NCT00113100 is an interventional study that assigns participants to a tested intervention. The registered 152 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).

The record links to 0 conditions, and to 1 intervention - of which Topical 17-beta estradiol in ethanol/propylene glycol (ETOH/PG) is the first listed.

NCT00113100 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00113100 about?

NCT00113100 is a clinical study titled "Mechanisms of Skin Repair by Topical Estrogen". The purpose of this study is to investigate the way by which estrogen improves the appearance of sun damaged human skin. Accumulating evidence suggests that estrogen, taken by post menopausal women, may cause skin to look younger as a consequence of reduced wrinkles. Collagen is the most abundant pr...

What is the current status of trial NCT00113100?

This trial is currently completed. It is a NA study. The enrollment target is 152 participants. The study started on 2004-08. Estimated completion is 2007-06.

What interventions are being tested in trial NCT00113100?

The interventions under investigation include: Topical 17-beta estradiol in ethanol/propylene glycol (ETOH/PG) (DRUG).

Who is sponsoring clinical trial NCT00113100?

This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00113100's enrollment target sits among peer trials

152 658th of 2000 higher than 1,340 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00113100, the US trial registry maintained by the National Library of Medicine. NCT00113100 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.