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NCT00112567 · ClinicalTrials.gov registry record · Phase 1

Total-Body Irradiation, Thiotepa, and Fludarabine in Treating Young Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer

A Phase 1 study, sponsored by Fred Hutchinson Cancer Center.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT00112567 is a Phase 1 study that has completed, run by Fred Hutchinson Cancer Center. The registered enrollment target is 20 participants.

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The verdict

NCT00112567, a Phase 1 study, has completed, sponsored by Fred Hutchinson Cancer Center.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

RATIONALE: Chemotherapy, such as fludarabine and thiotepa, and radiation therapy may destroy cancerous blood-forming cells (stem cells) in the blood and bone marrow. Giving healthy stem cells from a donor whose blood closely resembles the patient's blood will help the patient's bone marrow make new stem cells that become red blood cells, white blood cells, and platelets. PURPOSE: This phase I/II trial is studying the side effects of total-body irradiation, fludarabine, and thiotepa and to see how well they work in treating young patients who are undergoing a donor stem cell transplant for hematologic cancer.

Interventions

  • DRUG fludarabine phosphate
  • RADIATION radiation therapy
  • PROCEDURE peripheral blood stem cell transplantation
  • DRUG thiotepa

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2003-04
Est. Completion 2007-07
Phase Phase 1

Sponsor

Fred Hutchinson Cancer Center

483 total trials

What the Registry Record Tells You About NCT00112567

The ClinicalTrials.gov registry entry for NCT00112567 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which fludarabine phosphate is the first listed.

NCT00112567 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00112567 about?

NCT00112567 is a clinical study titled "Total-Body Irradiation, Thiotepa, and Fludarabine in Treating Young Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic Cancer". RATIONALE: Chemotherapy, such as fludarabine and thiotepa, and radiation therapy may destroy cancerous blood-forming cells (stem cells) in the blood and bone marrow. Giving healthy stem cells from a donor whose blood closely resembles the patient's blood will help the patient's bone marrow make new ...

What is the current status of trial NCT00112567?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2003-04. Estimated completion is 2007-07.

What interventions are being tested in trial NCT00112567?

The interventions under investigation include: fludarabine phosphate (DRUG), radiation therapy (RADIATION), peripheral blood stem cell transplantation (PROCEDURE), thiotepa (DRUG).

Who is sponsoring clinical trial NCT00112567?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.