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NCT00107861 · ClinicalTrials.gov registry record · Phase 1

Interferon-Beta Gene Transfer (Ad.hIFN-β) as Treatment for Refractory Colorectal Carcinoma With Liver Metastases

A Phase 1 study, sponsored by Biogen.

Completed
Registry status
Phase 1
Development phase
44
Enrollment target

NCT00107861: Completed Phase 1 study, sponsored by Biogen.

NCT00107861 is a Phase 1 study that has completed, run by Biogen. The registered enrollment target is 44 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00107861, a Phase 1 study, has completed, sponsored by Biogen.

COMPLETED
Registry status
Phase 1
Development phase
44 participants
Enrollment target

Study Summary

This study will be conducted in subjects with refractory colorectal carcinoma with unresectable liver metastases. The purposes of the study are: * to evaluate the safety and any harmful effects of an intravenous injection of Ad.hIFN-β; * help determine whether the virus carrying the interferon-beta gene will enter the bloodstream and liver tumor cells and cause the cancer cells to die.

Interventions

  • DRUG Ad.hIFN-β (BG00001, IDEC-201)

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2005-05
Est. Completion 2006-09
Phase Phase 1
Biogen

334 total trials

What the finished NCT00107861 record still lists

NCT00107861 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (27% lower).

The record links to 0 conditions, and to 1 intervention - of which Ad.hIFN-β (BG00001, IDEC-201) is the first listed.

NCT00107861 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00107861 about?

NCT00107861 is a clinical study titled "Interferon-Beta Gene Transfer (Ad.hIFN-β) as Treatment for Refractory Colorectal Carcinoma With Liver Metastases". This study will be conducted in subjects with refractory colorectal carcinoma with unresectable liver metastases. The purposes of the study are: * to evaluate the safety and any harmful effects of an intravenous injection of Ad.hIFN-β; * help determine whether the virus carrying the interferon-beta...

What is the current status of trial NCT00107861?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2005-05. Estimated completion is 2006-09.

What interventions are being tested in trial NCT00107861?

The interventions under investigation include: Ad.hIFN-β (BG00001, IDEC-201) (DRUG).

Who is sponsoring clinical trial NCT00107861?

This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00107861's enrollment target sits among peer trials

44 1086th of 2000 higher than 901 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00107861, the US trial registry maintained by the National Library of Medicine. NCT00107861 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.