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NCT00106184 · ClinicalTrials.gov registry record · Phase 2

Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)

A Phase 2 study, sponsored by University of Pittsburgh.

Completed
Registry status
Phase 2
Development phase
200
Enrollment target

NCT00106184 is a Phase 2 study that has completed, run by University of Pittsburgh. The registered enrollment target is 200 participants.

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The verdict

NCT00106184, a Phase 2 study, has completed, sponsored by University of Pittsburgh.

COMPLETED
Registry status
Phase 2
Development phase
200 participants
Enrollment target

Study Summary

Rituximab is a man-made antibody used to treat certain types of cancer. This study will determine whether rituximab is an effective treatment for adult and pediatric patients with dermatomyositis or polymyositis. Study hypotheses: 1) The time to improvement in Group A patients (receiving rituximab first) will occur significantly earlier than in Group B patients (receiving rituximab later). 2) The proportion of patients improved at Week 8 of the treatment phase will be significantly greater in Group A than in Group B.

Interventions

  • DRUG Placebo
  • DRUG Rituximab

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2006-03
Est. Completion 2010-08
Phase Phase 2

Sponsor

University of Pittsburgh

1,238 total trials

What the Registry Record Tells You About NCT00106184

The ClinicalTrials.gov registry entry for NCT00106184 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Pittsburgh, which has 1,238 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00106184 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00106184 about?

NCT00106184 is a clinical study titled "Rituximab for the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)". Rituximab is a man-made antibody used to treat certain types of cancer. This study will determine whether rituximab is an effective treatment for adult and pediatric patients with dermatomyositis or polymyositis. Study hypotheses: 1) The time to improvement in Group A patients (receiving rituximab ...

What is the current status of trial NCT00106184?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2006-03. Estimated completion is 2010-08.

What interventions are being tested in trial NCT00106184?

The interventions under investigation include: Placebo (DRUG), Rituximab (DRUG).

Who is sponsoring clinical trial NCT00106184?

This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.