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NCT00105027 · ClinicalTrials.gov registry record · Phase 3
The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study
A Phase 3 study, sponsored by The Emmes Company.
- Completed
- Registry status
- Phase 3
- Development phase
- 682
- Enrollment target
NCT00105027: Completed Phase 3 study, sponsored by The Emmes Company.
NCT00105027 is a Phase 3 study that has completed, run by The Emmes Company. The registered enrollment target is 682 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (12% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00105027, a Phase 3 study, has completed, sponsored by The Emmes Company.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 682 participants
- Enrollment target
Study Summary
The SCORE Study will compare the effectiveness and safety of standard care to intravitreal injection(s) of triamcinolone for treating macular edema (swelling of the central part of the retina) associated with central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO).
Primary Outcome
Visual acuity testing was done using electronic Early Treatment Diabetic Retinopathy Study (E-ETDRS) visual acuity testing at 3 meters using the Electronic Visual Acuity Tester by a SCORE certified technician. A masked visual acuity examiner with no knowledge of treatment assignments performed visual acuity testing at the 4-month, 12-month, 24-month and 36-month visits. An E-ETDRS visual acuity score of 85 is approximately 20/20, and a score of 20 letters is approximately 20/400. A visual acuity
Interventions
- OTHER Standard Care
- DRUG intravitreal triamcinolone injection
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 682 participants |
| Start Date | 2004-10 |
| Est. Completion | 2009-02 |
| Phase | Phase 3 |
What the finished NCT00105027 record still lists
NCT00105027 is an interventional study that assigns participants to a tested intervention. The registered 682 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (12% lower).
The record links to 0 conditions, and to 2 interventions - of which Standard Care is the first listed.
NCT00105027 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00105027 about?
NCT00105027 is a clinical study titled "The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study". The SCORE Study will compare the effectiveness and safety of standard care to intravitreal injection(s) of triamcinolone for treating macular edema (swelling of the central part of the retina) associated with central retinal vein occlusion (CRVO) and branch retinal vein occlusion (BRVO).
What is the current status of trial NCT00105027?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 682 participants. The study started on 2004-10. Estimated completion is 2009-02.
What interventions are being tested in trial NCT00105027?
The interventions under investigation include: Standard Care (OTHER), intravitreal triamcinolone injection (DRUG).
Who is sponsoring clinical trial NCT00105027?
This trial is sponsored by The Emmes Company, which has 11 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00105027's enrollment target sits among peer trials
682 529th of 2000 higher than 1,471 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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