Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00100737 · ClinicalTrials.gov registry record · Phase 2

Comparing Interleukin-2 (IL-2) Combined With Rituximab (Rituxan) to Rituximab Alone in Subjects With Non-Hodgkin's Lymphoma (NHL)

A Phase 2 study, sponsored by Chiron Corporation.

Terminated
Registry status
Phase 2
Development phase
300
Enrollment target

NCT00100737: Clinical Trial Phase 2 study, sponsored by Chiron Corporation.

NCT00100737 is a Phase 2 study that was terminated before completion, run by Chiron Corporation. The registered enrollment target is 300 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (126% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00100737, a Phase 2 study, was terminated before completion, sponsored by Chiron Corporation.

TERMINATED
Registry status
Phase 2
Development phase
300 participants
Enrollment target

Study Summary

The purpose of this study is to determine whether interleukin-2 given 3 times weekly for 8 weeks in combination with rituximab is effective and safe when compared to rituximab given alone in the treatment of follicular NHL subjects that have never received rituximab as a treatment and are refractory or relapsed after previous chemotherapy.

Interventions

  • DRUG rituximab
  • DRUG interleukin-2

Trial Details

FieldValue
Enrollment Target 300 participants
Phase Phase 2
Chiron Corporation

9 total trials

Why NCT00100737 stopped before completion

NCT00100737 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (126% higher).

The record links to 0 conditions, and to 2 interventions - of which rituximab is the first listed.

NCT00100737 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00100737 about?

NCT00100737 is a clinical study titled "Comparing Interleukin-2 (IL-2) Combined With Rituximab (Rituxan) to Rituximab Alone in Subjects With Non-Hodgkin's Lymphoma (NHL)". The purpose of this study is to determine whether interleukin-2 given 3 times weekly for 8 weeks in combination with rituximab is effective and safe when compared to rituximab given alone in the treatment of follicular NHL subjects that have never received rituximab as a treatment and are refractory...

What is the current status of trial NCT00100737?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 300 participants.

What interventions are being tested in trial NCT00100737?

The interventions under investigation include: rituximab (DRUG), interleukin-2 (DRUG).

Who is sponsoring clinical trial NCT00100737?

This trial is sponsored by Chiron Corporation, which has 9 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00100737's enrollment target sits among peer trials

300 167th of 2000 higher than 1,813 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00353483 · 300 participants

    Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells

  • NCT00588185 · 300 participants · NA

    [18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer

  • NCT00682032 · 300 participants · NA

    The Effect of Beta-glucan in Non-Small Cell Lung Cancer

  • NCT00870064 · 300 participants · NA

    The Treatment of Type I Open Fractures in Pediatrics

Source: ClinicalTrials.gov NCT00100737, the US trial registry maintained by the National Library of Medicine. NCT00100737 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.