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NCT00100685 · ClinicalTrials.gov registry record · Phase 2

Study of M200 (Volociximab) in Patients With Metastatic Renal Cell Carcinoma (RCC)

A Phase 2 study, sponsored by Abbott.

Terminated
Registry status
Phase 2
Development phase
48
Enrollment target

NCT00100685: Clinical Trial Phase 2 study, sponsored by Abbott.

NCT00100685 is a Phase 2 study that was terminated before completion, run by Abbott. The registered enrollment target is 48 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00100685, a Phase 2 study, was terminated before completion, sponsored by Abbott.

TERMINATED
Registry status
Phase 2
Development phase
48 participants
Enrollment target

Study Summary

This clinical trial is being conducted to determine tumor response and preliminary safety of a monoclonal antibody that specifically binds to a cell surface receptor (α5β1 integrin) and is required for the establishment of new blood vessels during tumor growth, a process known as angiogenesis.

Interventions

  • DRUG Volociximab (anti-α5β1 integrin monoclonal antibody)

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2005-01
Est. Completion 2007-12
Phase Phase 2
Abbott

181 total trials

Why NCT00100685 stopped before completion

NCT00100685 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower).

The record links to 0 conditions, and to 1 intervention - of which Volociximab (anti-α5β1 integrin monoclonal antibody) is the first listed.

NCT00100685 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00100685 about?

NCT00100685 is a clinical study titled "Study of M200 (Volociximab) in Patients With Metastatic Renal Cell Carcinoma (RCC)". This clinical trial is being conducted to determine tumor response and preliminary safety of a monoclonal antibody that specifically binds to a cell surface receptor (α5β1 integrin) and is required for the establishment of new blood vessels during tumor growth, a process known as angiogenesis.

What is the current status of trial NCT00100685?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 48 participants. The study started on 2005-01. Estimated completion is 2007-12.

What interventions are being tested in trial NCT00100685?

The interventions under investigation include: Volociximab (anti-α5β1 integrin monoclonal antibody) (DRUG).

Who is sponsoring clinical trial NCT00100685?

This trial is sponsored by Abbott, which has 181 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00100685's enrollment target sits among peer trials

48 1265th of 2000 higher than 718 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00100685, the US trial registry maintained by the National Library of Medicine. NCT00100685 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.