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NCT00087334 · ClinicalTrials.gov registry record · Phase 1

Capecitabine, Oxaliplatin, and Gefitinib in Treating Patients With Metastatic Colorectal Cancer

A Phase 1 study, sponsored by Roswell Park Cancer Institute.

Terminated
Registry status
Phase 1
Development phase
10
Enrollment target

NCT00087334: Clinical Trial Phase 1 study, sponsored by Roswell Park Cancer Institute.

NCT00087334 is a Phase 1 study that was terminated before completion, run by Roswell Park Cancer Institute. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00087334, a Phase 1 study, was terminated before completion, sponsored by Roswell Park Cancer Institute.

TERMINATED
Registry status
Phase 1
Development phase
10 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Gefitinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Combining capecitabine and oxaliplatin with gefitinib may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of capecitabine when given together with oxaliplatin and gefitinib and to see how well they work in treating patients with metastatic colorectal cancer.

Interventions

  • DRUG oxaliplatin
  • DRUG capecitabine
  • DRUG gefitinib

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2004-01
Phase Phase 1
Roswell Park Cancer Institute

365 total trials

Why NCT00087334 stopped before completion

NCT00087334 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 3 interventions - of which oxaliplatin is the first listed.

NCT00087334 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00087334 about?

NCT00087334 is a clinical study titled "Capecitabine, Oxaliplatin, and Gefitinib in Treating Patients With Metastatic Colorectal Cancer". RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Gefitinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Combining capecitabine and oxaliplatin w...

What is the current status of trial NCT00087334?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2004-01.

What interventions are being tested in trial NCT00087334?

The interventions under investigation include: oxaliplatin (DRUG), capecitabine (DRUG), gefitinib (DRUG).

Who is sponsoring clinical trial NCT00087334?

This trial is sponsored by Roswell Park Cancer Institute, which has 365 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00087334's enrollment target sits among peer trials

10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00087334, the US trial registry maintained by the National Library of Medicine. NCT00087334 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.