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NCT00087191 · ClinicalTrials.gov registry record · NA

EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer

A NA study, sponsored by National Cancer Institute (NCI).

Terminated
Registry status
NA
Development phase
30
Enrollment target

NCT00087191: Clinical Trial NA study, sponsored by National Cancer Institute (NCI).

NCT00087191 is a NA study that was terminated before completion, run by National Cancer Institute (NCI). The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00087191, a NA study, was terminated before completion, sponsored by National Cancer Institute (NCI).

TERMINATED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

This clinical trial is studying the amount of EF5 and motexafin lutetium present in tumor cells and/or normal tissues of patients with abdominal (such as ovarian, colon, or stomach cancer) or non-small cell lung cancer. EF5 may be effective in measuring oxygen in tumor tissue. Photosensitizing drugs such as motexafin lutetium are absorbed by tumor cells and, when exposed to light, become active and kill the tumor cells. Knowing the level of oxygen in tumor tissue and the level of motexafin lutetium absorbed by tumors and normal tissue may help predict the effectiveness of anticancer therapy

Primary Outcome

Data will be described using graphical techniques (e.g., box plots) and summary statistics (e.g., means, medians, standard deviations, and interquartile ranges). For each patient, the mean concentration of motexafin lutetium across tumor and normal samples will be summarized.

Interventions

  • OTHER pharmacological study
  • DRUG EF5
  • DRUG motexafin lutetium

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2004-05
Phase NA
National Cancer Institute (NCI)

3,257 total trials

Why NCT00087191 stopped before completion

NCT00087191 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 3 interventions - of which pharmacological study is the first listed.

NCT00087191 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00087191 about?

NCT00087191 is a clinical study titled "EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung Cancer". This clinical trial is studying the amount of EF5 and motexafin lutetium present in tumor cells and/or normal tissues of patients with abdominal (such as ovarian, colon, or stomach cancer) or non-small cell lung cancer. EF5 may be effective in measuring oxygen in tumor tissue. Photosensitizing drugs...

What is the current status of trial NCT00087191?

This trial is currently terminated. It is a NA study. The enrollment target is 30 participants. The study started on 2004-05.

What interventions are being tested in trial NCT00087191?

The interventions under investigation include: pharmacological study (OTHER), EF5 (DRUG), motexafin lutetium (DRUG).

Who is sponsoring clinical trial NCT00087191?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00087191's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00087191, the US trial registry maintained by the National Library of Medicine. NCT00087191 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.