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NCT00086190 · ClinicalTrials.gov registry record · Phase 3
Study of Antidepressants in Parkinson's Disease
A Phase 3 study, sponsored by University of Rochester.
- Completed
- Registry status
- Phase 3
- Development phase
- 115
- Enrollment target
NCT00086190: Completed Phase 3 study, sponsored by University of Rochester.
NCT00086190 is a Phase 3 study that has completed, run by University of Rochester. The registered enrollment target is 115 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00086190, a Phase 3 study, has completed, sponsored by University of Rochester.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 115 participants
- Enrollment target
Study Summary
The purpose of this study is to find out if two antidepressant medications, paroxetine and venlafaxine, can help control depression in Parkinson's disease, and if these medications affect the motor symptoms of Parkinson's disease such as tremor, stiffness, slowness, and balance.
Primary Outcome
Change in Hamilton Rating Scale for Depression over 12 weeks. Hamilton Depression Rating Scale ranges from 0-50. Higher scores represent more significant depression. Mild depression ranges from 8-13, moderate depression from 14-18, severe 19-22 and very severe any score over 23.
Interventions
- OTHER placebo
- DRUG venlafaxine
- DRUG paroxetine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 115 participants |
| Start Date | 2005-06 |
| Est. Completion | 2009-11 |
| Phase | Phase 3 |
What the finished NCT00086190 record still lists
NCT00086190 is an interventional study that assigns participants to a tested intervention. The registered 115 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (85% lower).
The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.
NCT00086190 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00086190 about?
NCT00086190 is a clinical study titled "Study of Antidepressants in Parkinson's Disease". The purpose of this study is to find out if two antidepressant medications, paroxetine and venlafaxine, can help control depression in Parkinson's disease, and if these medications affect the motor symptoms of Parkinson's disease such as tremor, stiffness, slowness, and balance.
What is the current status of trial NCT00086190?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 115 participants. The study started on 2005-06. Estimated completion is 2009-11.
What interventions are being tested in trial NCT00086190?
The interventions under investigation include: placebo (OTHER), venlafaxine (DRUG), paroxetine (DRUG).
Who is sponsoring clinical trial NCT00086190?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00086190's enrollment target sits among peer trials
115 1644th of 2000 higher than 353 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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