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NCT00085787 · ClinicalTrials.gov registry record · Phase 1

A Study of ARRY-142886 in Patients With Advanced Cancer

A Phase 1 study, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.

Completed
Registry status
Phase 1
Development phase
57
Enrollment target

NCT00085787: Completed Phase 1 study, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.

NCT00085787 is a Phase 1 study that has completed, run by Array Biopharma, now a wholly owned subsidiary of Pfizer. The registered enrollment target is 57 participants, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00085787, a Phase 1 study, has completed, sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer.

COMPLETED
Registry status
Phase 1
Development phase
57 participants
Enrollment target

Study Summary

This is a Phase 1 study during which patients with advanced solid tumors will receive investigational study drug ARRY-142886. This study has 2 parts. In the first part, patients will receive increasing doses of study drug in order to achieve the highest dose of study drug possible that will not cause unacceptable side effects. Approximately 25 patients from the US will be enrolled in Part 1 (Completed). In the second part of the study, patients will receive the best dose of study drug, determined from the first part of the study, and will be followed to see what side effects the study drug causes and what effectiveness the study drug has, if any, in treating the cancer. Approximately 35 patients from the US will be enrolled in Part 2 (Completed).

Interventions

  • DRUG ARRY-142886, MEK inhibitor; oral

Trial Details

FieldValue
Enrollment Target 57 participants
Start Date 2004-06
Est. Completion 2007-02
Phase Phase 1

What the finished NCT00085787 record still lists

NCT00085787 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 57 participants, a relatively small participant target, roughly in line with the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which ARRY-142886, MEK inhibitor; oral is the first listed.

NCT00085787 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00085787 about?

NCT00085787 is a clinical study titled "A Study of ARRY-142886 in Patients With Advanced Cancer". This is a Phase 1 study during which patients with advanced solid tumors will receive investigational study drug ARRY-142886. This study has 2 parts. In the first part, patients will receive increasing doses of study drug in order to achieve the highest dose of study drug possible that will not cau...

What is the current status of trial NCT00085787?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 57 participants. The study started on 2004-06. Estimated completion is 2007-02.

What interventions are being tested in trial NCT00085787?

The interventions under investigation include: ARRY-142886, MEK inhibitor; oral (DRUG).

Who is sponsoring clinical trial NCT00085787?

This trial is sponsored by Array Biopharma, now a wholly owned subsidiary of Pfizer, which has 21 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00085787's enrollment target sits among peer trials

57 901st of 2000 higher than 1,099 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00085787, the US trial registry maintained by the National Library of Medicine. NCT00085787 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.