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NCT00085384 · ClinicalTrials.gov registry record · Phase 1

PEG-Interferon Alfa-2b in Treating Patients With Platinum-Resistant Ovarian Epithelial, Peritoneal, or Fallopian Tube Cancer

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
Phase 1
Development phase
30
Enrollment target

NCT00085384: Clinical Trial Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT00085384 is a Phase 1 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00085384, a Phase 1 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

RATIONALE: PEG-interferon alfa-2b may interfere with the growth of cancer cells. PURPOSE: This randomized phase I/II trial is studying the side effects and best dose of PEG-interferon alfa-2b and to see how well it works in treating patients with ovarian epithelial, peritoneal, or fallopian tube cancer that is resistant to platinum-based chemotherapy.

Primary Outcome

Optimum biologic dose of PEG Intron in patients with platinum-resistant ovarian, fallopian tube or peritoneal cancer whose tumors test positive for IL-8, BFGF, or VEGF.

Interventions

  • BIOLOGICAL PEG-interferon alfa-2b
  • DRUG PEG-interferon alfa-2b

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2002-07
Est. Completion 2007-04
Phase Phase 1
M.D. Anderson Cancer Center

2,692 total trials

Why NCT00085384 stopped before completion

NCT00085384 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 2 interventions - of which PEG-interferon alfa-2b is the first listed.

NCT00085384 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00085384 about?

NCT00085384 is a clinical study titled "PEG-Interferon Alfa-2b in Treating Patients With Platinum-Resistant Ovarian Epithelial, Peritoneal, or Fallopian Tube Cancer". RATIONALE: PEG-interferon alfa-2b may interfere with the growth of cancer cells. PURPOSE: This randomized phase I/II trial is studying the side effects and best dose of PEG-interferon alfa-2b and to see how well it works in treating patients with ovarian epithelial, peritoneal, or fallopian tube ca...

What is the current status of trial NCT00085384?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2002-07. Estimated completion is 2007-04.

What interventions are being tested in trial NCT00085384?

The interventions under investigation include: PEG-interferon alfa-2b (BIOLOGICAL), PEG-interferon alfa-2b (DRUG).

Who is sponsoring clinical trial NCT00085384?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00085384's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00085384, the US trial registry maintained by the National Library of Medicine. NCT00085384 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.