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NCT00084617 · ClinicalTrials.gov registry record · Phase 2

Phase II Study of Oxaliplatin, Irinotecan, and Capecitabine in Advanced Gastric/Gastroesophageal Junction Carcinoma

A Phase 2 study, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 2
Development phase
39
Enrollment target

NCT00084617: Completed Phase 2 study, sponsored by National Cancer Institute (NCI).

NCT00084617 is a Phase 2 study that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 39 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00084617, a Phase 2 study, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 2
Development phase
39 participants
Enrollment target

Study Summary

Drugs used in chemotherapy, such as oxaliplatin, irinotecan, and capecitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one chemotherapy drug may kill more tumor cells. This phase II trial is studying how well giving oxaliplatin together with irinotecan and capecitabine works in treating patients with metastatic or inoperable locally advanced gastric cancer or gastroesophageal junction adenocarcinoma (cancer).

Primary Outcome

Response is defined as the number of patients with a CR (Complete Response) or PR (Partial Response) per Response Evaluation Criteria in Solid Tumor (RECIST criteria). Possible evaluations include: CR: Disappearance of all target lesions. PR: At least a 30% decrease in the size of target lesions. Progressive Disease (PD): At least a 20% increase in the size of the target lesions or appearance of one or more new lesions. Stable Disease (SD): Neither sufficient shrinkage or increase of target lesi

Interventions

  • DRUG oxaliplatin
  • DRUG capecitabine
  • DRUG irinotecan hydrochloride

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2004-03
Est. Completion 2008-12
Phase Phase 2
National Cancer Institute (NCI)

3,257 total trials

What the finished NCT00084617 record still lists

NCT00084617 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (71% lower).

The record links to 0 conditions, and to 3 interventions - of which oxaliplatin is the first listed.

NCT00084617 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00084617 about?

NCT00084617 is a clinical study titled "Phase II Study of Oxaliplatin, Irinotecan, and Capecitabine in Advanced Gastric/Gastroesophageal Junction Carcinoma". Drugs used in chemotherapy, such as oxaliplatin, irinotecan, and capecitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one chemotherapy drug may kill more tumor cells. This phase II trial is studying how well giving oxaliplatin together ...

What is the current status of trial NCT00084617?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 39 participants. The study started on 2004-03. Estimated completion is 2008-12.

What interventions are being tested in trial NCT00084617?

The interventions under investigation include: oxaliplatin (DRUG), capecitabine (DRUG), irinotecan hydrochloride (DRUG).

Who is sponsoring clinical trial NCT00084617?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00084617's enrollment target sits among peer trials

39 1459th of 2000 higher than 534 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00084617, the US trial registry maintained by the National Library of Medicine. NCT00084617 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.