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NCT00084058 · ClinicalTrials.gov registry record · Phase 1

Safety of Saquinavir and High Doses of Lopinavir/Ritonavir in Children With HIV

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
26
Enrollment target

NCT00084058: Completed Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00084058 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 26 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00084058, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
26 participants
Enrollment target

Study Summary

The purpose of this study is to determine the effect of increased doses of lopinavir/ritonavir (LPV/r) and saquinavir (SQV) in HIV infected children who are failing their current antiretroviral regimen

Interventions

  • DRUG Saquinavir
  • DRUG Lopinavir/ritonavir

Trial Details

FieldValue
Enrollment Target 26 participants
Est. Completion 2006-12
Phase Phase 1

What the finished NCT00084058 record still lists

NCT00084058 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 26 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (57% lower).

The record links to 0 conditions, and to 2 interventions - of which Saquinavir is the first listed.

NCT00084058 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00084058 about?

NCT00084058 is a clinical study titled "Safety of Saquinavir and High Doses of Lopinavir/Ritonavir in Children With HIV". The purpose of this study is to determine the effect of increased doses of lopinavir/ritonavir (LPV/r) and saquinavir (SQV) in HIV infected children who are failing their current antiretroviral regimen

What is the current status of trial NCT00084058?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. Estimated completion is 2006-12.

What interventions are being tested in trial NCT00084058?

The interventions under investigation include: Saquinavir (DRUG), Lopinavir/ritonavir (DRUG).

Who is sponsoring clinical trial NCT00084058?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00084058's enrollment target sits among peer trials

26 1482nd of 2000 higher than 506 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00084058, the US trial registry maintained by the National Library of Medicine. NCT00084058 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.