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NCT00079339 · ClinicalTrials.gov registry record · Phase 1

Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma

A Phase 1 study of Untreated Childhood Brain Stem Glioma, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
51
Enrollment target
1
Study location

NCT00079339 is a Phase 1 study of Untreated Childhood Brain Stem Glioma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 51 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT00079339, a Phase 1 study of Untreated Childhood Brain Stem Glioma, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
51 participants
Enrollment target
1
Study location

Study Summary

Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Radiation therapy uses high-energy x-rays to damage tumor cells. Tipifarnib may make tumor cells more sensitive to radiation therapy. Combining tipifarnib with radiation therapy may kill more tumor cells. This phase I/II trial is studying the side effects and best dose of tipifarnib to see how well it works when given together with radiation therapy in treating young patients with newly diagnosed brain stem glioma. (Phase I closed to accrual as of 1/19/06)

Interventions

  • RADIATION radiation therapy
  • DRUG tipifarnib

Study Locations (1)

Tennessee

  • Pediatric Brain Tumor Consortium - Memphis

Trial Details

FieldValue
Enrollment Target 51 participants
Start Date 2004-01
Est. Completion 2009-11
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00079339

The ClinicalTrials.gov registry entry for NCT00079339 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 51 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Untreated Childhood Brain Stem Glioma appearing as the primary indexed condition, and to 2 interventions - of which radiation therapy is the first listed.

NCT00079339 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT00079339 about?

NCT00079339 is a clinical study titled "Tipifarnib and Radiation Therapy in Treating Young Patients With Brainstem Glioma". Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Radiation therapy uses high-energy x-rays to damage tumor cells. Tipifarnib may make tumor cells more sensitive to radiation therapy. Combining tipifarnib with radiation therapy may kill more tumor cell...

What is the current status of trial NCT00079339?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 51 participants. The study started on 2004-01. Estimated completion is 2009-11.

What conditions does trial NCT00079339 study?

This clinical trial studies the following conditions: Untreated Childhood Brain Stem Glioma.

What interventions are being tested in trial NCT00079339?

The interventions under investigation include: radiation therapy (RADIATION), tipifarnib (DRUG).

Who is sponsoring clinical trial NCT00079339?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00079339 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.