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NCT00076219 · ClinicalTrials.gov registry record · Phase 3
Acute Renal Failure Trial Network (ATN) Study
A Phase 3 study, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,124
- Enrollment target
NCT00076219: Completed Phase 3 study, sponsored by US Department of Veterans Affairs.
NCT00076219 is a Phase 3 study that has completed, run by US Department of Veterans Affairs. The registered enrollment target is 1,124 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (46% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00076219, a Phase 3 study, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,124 participants
- Enrollment target
Study Summary
This is a multi-center, prospective, randomized, parallel-group trial of an intensive strategy vs conventional strategy of renal replacement therapy for the treatment of acute renal failure secondary to acute tubular necrosis in critically ill patients. The primary hypothesis is that the intensive strategy will reduce 60-day all cause mortality by 10% compared to the conventional strategy - i.e.,a reduction from 55% in the conventional arm to 45% in the intensive arm. Secondary outcomes are 60-day in-hospital all-cause mortality, 1-year all cause mortality, and recovery of renal function by day 28. The study will recruit 1164 patients over a period of 3 years, 8 months and each patient will be actively followed for 60 days.
Primary Outcome
60-day all-cause mortality
Interventions
- PROCEDURE renal replacement therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,124 participants |
| Start Date | 2003-10 |
| Est. Completion | 2008-07 |
| Phase | Phase 3 |
What the finished NCT00076219 record still lists
NCT00076219 is an interventional study that assigns participants to a tested intervention. Its 1,124 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (46% higher).
The record links to 0 conditions, and to 1 intervention - of which renal replacement therapy is the first listed.
NCT00076219 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00076219 about?
NCT00076219 is a clinical study titled "Acute Renal Failure Trial Network (ATN) Study". This is a multi-center, prospective, randomized, parallel-group trial of an intensive strategy vs conventional strategy of renal replacement therapy for the treatment of acute renal failure secondary to acute tubular necrosis in critically ill patients. The primary hypothesis is that the intensive s...
What is the current status of trial NCT00076219?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,124 participants. The study started on 2003-10. Estimated completion is 2008-07.
What interventions are being tested in trial NCT00076219?
The interventions under investigation include: renal replacement therapy (PROCEDURE).
Who is sponsoring clinical trial NCT00076219?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00076219's enrollment target sits among peer trials
1,124 248th of 2000 higher than 1,753 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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