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NCT00075933 · ClinicalTrials.gov registry record · Phase 1

ARQ 501 in Subjects With Cancer

A Phase 1 study of Cancer, sponsored by ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA).

Completed
Registry status
Phase 1
Development phase
80
Enrollment target
2
Study locations

NCT00075933 is a Phase 1 study of Cancer that has completed, run by ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA). The registered enrollment target is 80 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (98% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT00075933, a Phase 1 study of Cancer, has completed, sponsored by ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA).

COMPLETED
Registry status
Phase 1
Development phase
80 participants
Enrollment target
2
Study locations

Study Summary

ARQ 501, an investigational anticancer drug, is intended to selectively kill cancer cells and spare normal cells by restoring and activating cellular checkpoints known to be defective in cancer using the Company's unique biology platform, Activated Checkpoint Therapy™ (ACT). ARQ 501 has the potential for improved activity and reduced toxicity over other molecular approaches and traditional cancer chemotherapy.

Conditions Studied

Interventions

  • DRUG ARQ 501

Study Locations (2)

Massachusetts

  • Dana Farber/Partners CancerCare Inc - Boston

Texas

  • Mary Crowley Medical Research Center - Dallas

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2003-09
Est. Completion 2007-01
Phase Phase 1

What the Registry Record Tells You About NCT00075933

The ClinicalTrials.gov registry entry for NCT00075933 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (98% lower). The listed sponsor is ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA), which has 27 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 1 intervention - of which ARQ 501 is the first listed.

NCT00075933 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Massachusetts, Texas.

Frequently Asked Questions

What is clinical trial NCT00075933 about?

NCT00075933 is a clinical study titled "ARQ 501 in Subjects With Cancer". ARQ 501, an investigational anticancer drug, is intended to selectively kill cancer cells and spare normal cells by restoring and activating cellular checkpoints known to be defective in cancer using the Company's unique biology platform, Activated Checkpoint Therapy™ (ACT). ARQ 501 has the potenti...

What is the current status of trial NCT00075933?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2003-09. Estimated completion is 2007-01.

What conditions does trial NCT00075933 study?

This clinical trial studies the following conditions: Cancer.

What interventions are being tested in trial NCT00075933?

The interventions under investigation include: ARQ 501 (DRUG).

Who is sponsoring clinical trial NCT00075933?

This trial is sponsored by ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA), which has 27 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00075933 being conducted?

This trial has 2 study locations across Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.