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NCT00075621 · ClinicalTrials.gov registry record · Phase 2

Tandem Autologous Stem Cell Transplantation in Treating Patients With Primary Systemic (AL) Amyloidosis

A Phase 2 study, sponsored by Boston Medical Center.

Completed
Registry status
Phase 2
Development phase
62
Enrollment target

NCT00075621: Completed Phase 2 study, sponsored by Boston Medical Center.

NCT00075621 is a Phase 2 study that has completed, run by Boston Medical Center. The registered enrollment target is 62 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00075621, a Phase 2 study, has completed, sponsored by Boston Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
62 participants
Enrollment target

Study Summary

RATIONALE: Autologous stem cell transplantation may be effective treatment for primary systemic (AL) amyloidosis. PURPOSE: This phase II trial is studying how well tandem (two) autologous stem cell transplantation works in treating patients with primary systemic (AL) amyloidosis.

Interventions

  • DRUG melphalan
  • DRUG filgrastim
  • PROCEDURE autologous peripheral blood stem cell transplantation

Trial Details

FieldValue
Enrollment Target 62 participants
Start Date 2000-08
Est. Completion 2020-09-04
Phase Phase 2
Boston Medical Center

253 total trials

What the finished NCT00075621 record still lists

NCT00075621 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 62 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (53% lower).

The record links to 0 conditions, and to 3 interventions - of which melphalan is the first listed.

NCT00075621 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00075621 about?

NCT00075621 is a clinical study titled "Tandem Autologous Stem Cell Transplantation in Treating Patients With Primary Systemic (AL) Amyloidosis". RATIONALE: Autologous stem cell transplantation may be effective treatment for primary systemic (AL) amyloidosis. PURPOSE: This phase II trial is studying how well tandem (two) autologous stem cell transplantation works in treating patients with primary systemic (AL) amyloidosis.

What is the current status of trial NCT00075621?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 62 participants. The study started on 2000-08. Estimated completion is 2020-09-04.

What interventions are being tested in trial NCT00075621?

The interventions under investigation include: melphalan (DRUG), filgrastim (DRUG), autologous peripheral blood stem cell transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00075621?

This trial is sponsored by Boston Medical Center, which has 253 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00075621's enrollment target sits among peer trials

62 1016th of 2000 higher than 975 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00075621, the US trial registry maintained by the National Library of Medicine. NCT00075621 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.