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NCT00074607 · ClinicalTrials.gov registry record · Phase 1
Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine
A Phase 1 study, sponsored by Baylor College of Medicine.
- Terminated
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT00074607: Clinical Trial Phase 1 study, sponsored by Baylor College of Medicine.
NCT00074607 is a Phase 1 study that was terminated before completion, run by Baylor College of Medicine. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00074607, a Phase 1 study, was terminated before completion, sponsored by Baylor College of Medicine.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
Subject's are being asked to take part in this study because he or she has a type of cancer that has spread to the meninges (tissues that cover the brain and spinal cord). There is no known effective treatment for this specific disease or the subject has received all of the treatments that are known to work for his or her specific disease without success. Currently, there is no other effective treatment for this type of cancer. The purposes of this study are: * to determine the highest dose of gemcitabine, an anti-cancer drug, that can safely be given directly into the spinal fluid of children and adults whose cancer no longer responds to standard treatment; * to find out what effects (good and bad) gemcitabine has when given directly into the cerebrospinal fluid (called intrathecal administration) in children and adults with neoplastic meningitis (cancer that has spread to the lining of the brain and spinal cord); * to determine if gemcitabine is beneficial to the patient; * to understand how gemcitabine is handled by the body after intrathecal administration.
Interventions
- DRUG Gemcitabine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2001-12 |
| Est. Completion | 2007-04 |
| Phase | Phase 1 |
Why NCT00074607 stopped before completion
NCT00074607 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which Gemcitabine is the first listed.
NCT00074607 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00074607 about?
NCT00074607 is a clinical study titled "Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine". Subject's are being asked to take part in this study because he or she has a type of cancer that has spread to the meninges (tissues that cover the brain and spinal cord). There is no known effective treatment for this specific disease or the subject has received all of the treatments that are know...
What is the current status of trial NCT00074607?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2001-12. Estimated completion is 2007-04.
What interventions are being tested in trial NCT00074607?
The interventions under investigation include: Gemcitabine (DRUG).
Who is sponsoring clinical trial NCT00074607?
This trial is sponsored by Baylor College of Medicine, which has 616 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00074607's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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